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==Toxicity== {{Chembox |container_only = yes |Section7={{Chembox Hazards | ExternalSDS = | GHSPictograms = {{GHS02}} {{GHS05}} {{GHS06}} | GHSSignalWord = Danger | HPhrases = {{H-phrases|H228|H260|H301|H314}} | PPhrases = {{P-phrases|P210|P231 + P232|P260|P280|P303 + P361 + P353|P304 + P340 + P310|P305 + P351 + P338}} | GHS_ref = <ref>{{Cite web |url=https://www.sigmaaldrich.com/catalog/product/aldrich/237094?lang=en®ion=US |title=Barium 237094|publisher=Sigma-Aldrich|date=2021-10-28|access-date=2021-12-21}}<!-- date=rev.date s.-a. SDS form --></ref> | NFPA-H = 3 | NFPA-F = 3 | NFPA-R = 1 | NFPA-S = w | NFPA_ref = }} }} Soluble barium compounds have [[LD50]] near 10 mg/kg (oral rats). Symptoms include "convulsions... paralysis of the peripheral nerve system ... severe inflammation of the gastrointestinal tract".<ref name="Ullman2005" />{{rp|18}} The insoluble sulfate is nontoxic and is not classified as a [[dangerous goods]] in transport regulations.<ref name="Ullman2005" />{{rp|9}} Little is known about the long term effects of barium exposure.<ref>{{Cite journal |last1=Kravchenko |first1=Julia |last2=Darrah |first2=Thomas H. |last3=Miller |first3=Richard K. |last4=Lyerly |first4=H. Kim |last5=Vengosh |first5=Avner |date=August 2014 |title=A review of the health impacts of barium from natural and anthropogenic exposure |url=http://link.springer.com/10.1007/s10653-014-9622-7 |journal=Environmental Geochemistry and Health |language=en |volume=36 |issue=4 |pages=797β814 |doi=10.1007/s10653-014-9622-7 |pmid=24844320 |bibcode=2014EnvGH..36..797K |issn=0269-4042}}</ref> The US [[EPA]] considers it unlikely that barium is carcinogenic when consumed orally. Inhaled dust containing insoluble barium compounds can accumulate in the lungs, causing a [[benign]] condition called [[baritosis]].<ref name="pmid1257935">{{cite journal |author=Doig, A. T. |title=Baritosis: a benign pneumoconiosis |journal=Thorax |volume=31 |issue=1 |pages=30β9 |date=1976 |pmid=1257935 |pmc=470358 |doi= 10.1136/thx.31.1.30}}</ref> [[Barium carbonate]] has been used as a rodenticide.<ref name=clarkson> {{Cite book |first=Thomas W.|last=Clarkson |chapter=Chapter 61 - Inorganic and Organometal Pesticides |editor-first1=Robert I.|editor-last1=Krieger |editor-first2=William C.|editor-last2=Krieger |title=Handbook of Pesticide Toxicology |publisher=Academic Press |year=2001 |page=1357 |edition=Second |isbn=9780124262607 |doi=10.1016/B978-012426260-7.50064-1 }}</ref> Though considered obsolete, it may still be in use in some countries.<ref>{{cite web | url=https://sitem.herts.ac.uk/aeru/ppdb/en/Reports/2704.htm | website=Pesticide Properties Database | title=Barium carbonate }}</ref>
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