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==Genetics== {{See also|Sintashta culture#Genetics|Andronovo culture#Genetics}} {{multiple image | align = right | direction = vertical | width = 231 | image1 = Genetic proximity of Eastern Indo-Europeans.png | caption1 = Genetic proximity of Eastern Indo-Europeans: the Wusun had great genetic proximity with the [[Kangju]], the [[Andronovo]], the [[Sarmatians]], the [[Sakas]] or the [[Tagar culture|Tagar]] populations.<ref>{{cite journal |last1=Zhang |first1=Fan|title=The genomic origins of the Bronze Age Tarim Basin mummies |journal=Nature |date=November 2021 |volume=599 |issue=7884 |pages=256–261 |doi=10.1038/s41586-021-04052-7 |pmid=34707286 |language=en |issn=1476-4687|pmc=8580821 |bibcode=2021Natur.599..256Z }}</ref> | image2 = Scythian genetic makeup.png | caption2 = Genetic makeup of Iron Age Central Asian Scythians. The three main ancestry components are shown in green, red and violet representing the ancestries maximized in [[Anatolian Neolithic Farmers|Anatolian farmers]], [[Ganj Dareh|Iranian farmers]], and [[West Siberian hunter-gatherer|Hunter Gatherers from West Siberia]], respectively. }} A genetic study published in ''[[Nature (journal)|Nature]]'' in May 2018 examined the remains of four Wusun buried between {{Circa}} 300 BC and 100 BC. The sample of [[Y-DNA]] extracted belonged to [[haplogroup R1]]. The samples of [[mtDNA]] extracted belonged to [[Haplogroup C (mtDNA)|C4a1]], [[Haplogroup HV (mtDNA)|HV6]], [[Haplogroup J (mtDNA)|J1c5a]] and [[Haplogroup U (mtDNA)#Haplogroup U5|U5b2c]]. The authors of the study found that the Wusun and [[Kangju]] had less [[East Asian people|East Asian]] mixture than the [[Xiongnu]] and the [[Saka]]. Both the Wusun and Kangju were suggested to be descended from [[Western Steppe Herders]] of the Late Bronze Age who admixed with Siberian hunter-gatherers and peoples related to the [[Bactria–Margiana Archaeological Complex]].{{sfn|Damgaard et al.|2018}} One theory has suggested that the Uissun tribe of Kazakhstan is descended from the Wusun, based on the superficial similarity of the ethnonym 'Uissun' to Wusun.<ref>{{cite book |last1=Tynyshpaev |first1=M |title=Materials on the history of Kyrgyz-kazakh people. Tashkent: Eastern branch of the Kyrgyz State |date=1925 |publisher=Kyrgyz State Publishing |location=Tashkent |page=77}}</ref> A 2020 study could not find support for this theory, as the Uissun have a very low frequency of Haplogroup R1a (6%), most of it belonging to the Z94 clade rather than the Iranian Z93 clade.{{sfn|Zhabagin et al.|2020}} Most of the Uissun lineages were typical of Mongols, supporting their historically attested Mongolian origin.<ref>{{cite book |last1=Al-Din |first1=Rashid |title=Collection of histories. Volume 1, Book 1. |date=1952 |publisher=Publishing House of the Academy of Sciences of the USSR |location=Moscow-Leningrad |page=151}}</ref>
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