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==Medical uses== {{see|Pyridoxine}} [[Isoniazid]] is an [[antibiotic]] used for the treatment of [[tuberculosis]]. A common side effect is numbness in the hands and feet, also known as [[peripheral neuropathy]].<ref name=AHFS2016>{{cite web|title=Isoniazid|url=https://www.drugs.com/monograph/isoniazid.html|publisher=The American Society of Health-System Pharmacists|access-date=August 13, 2021|archive-date=December 20, 2016|archive-url=https://web.archive.org/web/20161220231039/https://www.drugs.com/monograph/isoniazid.html|url-status=live}}</ref> Co-treatment with vitamin B<sub>6</sub> alleviates the numbness.<ref name="Lheureux2005">{{cite journal |vauthors=Lheureux P, Penaloza A, Gris M |title=Pyridoxine in clinical toxicology: a review |journal=Eur J Emerg Med |volume=12 |issue=2 |pages=78β85 |date=April 2005 |pmid=15756083 |doi=10.1097/00063110-200504000-00007 |s2cid=39197646 |url=}}</ref> Overconsumption of seeds from ''[[Ginkgo biloba]]'' can deplete vitamin B<sub>6</sub>, because the [[ginkgotoxin]] is an anti-vitamin (vitamin antagonist). Symptoms include vomiting and generalized convulsions. Ginkgo seed poisoning can be treated with vitamin B<sub>6</sub>.<ref>{{cite journal |vauthors=Mei N, Guo X, Ern Z, Kobayashi D, Wada K, Guo L |title=Review of ''Ginkgo biloba''-induced toxicity, from experimental studies to human case reports |journal=J Environ Sci Health C Environ Carcinog Ecotoxicol Rev |volume=35 |issue=1 |pages=1β28 |date=January 2017 |pmid=28055331 |pmc=6373469 |doi=10.1080/10590501.2016.1278298 |bibcode=2017JESHC..35....1M |url=}}</ref><ref>{{cite journal |vauthors=Kobayashi D |title=[Food Poisoning by Ginkgo Seeds through Vitamin B6 Depletion] |language=Japanese |journal=Yakugaku Zasshi |volume=139 |issue=1 |pages=1β6 |date=2019 |pmid=30606915 |doi=10.1248/yakushi.18-00136 |url=|doi-access=free }}</ref>
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