Editing Skin (section)

==== Granular glands ====
Granular glands can be identified as [[venom]]ous and often differ in the type of toxin as well as the concentrations of secretions across various orders and species within the amphibians. They are located in clusters differing in concentration depending on [[amphibian]] taxa. The toxins can be fatal to most vertebrates or have no effect against others. These glands are alveolar meaning they structurally have little sacs in which venom is produced and held before it is secreted upon defensive behaviors.<ref name=":0" />

Structurally, the ducts of the granular gland initially maintain a cylindrical shape. When the ducts mature and fill with fluid, the base of the ducts become swollen due to the pressure from the inside. This causes the epidermal layer to form a pit like opening on the surface of the duct in which the inner fluid will be secreted in an upwards fashion.<ref name=":1">{{cite journal |last1=Dawson |first1=A. B. |title=The integument of necturus maculosus |journal=Journal of Morphology |date=December 1920 |volume=34 |issue=3 |pages=486–589 |doi=10.1002/jmor.1050340303 |s2cid=83534922 |url=https://books.google.com/books?id=UklQAQAAMAAJ&pg=PA487}}</ref>

The intercalary region of granular glands is more developed and mature in comparison with mucous glands. This region resides as a ring of cells surrounding the basal portion of the duct which are argued to have an [[ectoderm]]al muscular nature due to their influence over the lumen (space inside the tube) of the duct with dilation and constriction functions during secretions. The cells are found radially around the duct and provide a distinct attachment site for muscle fibers around the gland's body.<ref name=":1" />

The gland alveolus is a sac that is divided into three specific regions/layers. The outer layer or tunica fibrosa is composed of densely packed connective-tissue which connects with fibers from the spongy intermediate layer where elastic fibers, as well as nerves, reside. The nerves send signals to the muscles as well as the epithelial layers. Lastly, the epithelium or tunica propria encloses the gland.<ref name=":1" />