Editing Rotavirus (section)

=== Markers of protection ===
The levels of IgG and IgA in the blood and IgA in the gut correlate with protection from infection.<ref name="pmid7817873">{{cite journal |vauthors=Offit PA |title=Rotaviruses: immunological determinants of protection against infection and disease |journal=Advances in Virus Research |volume=44 |issue= |pages=161–202 |date=1994 |pmid=7817873 |pmc=7130874 |doi=10.1016/s0065-3527(08)60329-2 |isbn=978-0-12-039844-7 }}</ref> Rotavirus specific serum IgG and IgA at high [[titre]]s (e.g. >1:200) have been claimed to be protective and there is a significant correlation between IgA titres and rotavirus vaccine efficacy.<ref name="pmid23596320">{{cite journal |vauthors=Patel M, Glass RI, Jiang B, Santosham M, Lopman B, Parashar U |title=A systematic review of anti-rotavirus serum IgA antibody titer as a potential correlate of rotavirus vaccine efficacy |journal=The Journal of Infectious Diseases |volume=208 |issue=2 |pages=284–294 |year=2013 |pmid=23596320 |doi=10.1093/infdis/jit166 |doi-access=free }}</ref>