Editing Phencyclidine (section)

==History==
Phencyclidine was initially discovered in 1926 by {{ill|Arthur Kötz|de}} and his student Paul Merkel as a product of a [[Grignard reaction]] of 1-piperidinocyclohexancarbonitrile.<ref name="Kötz_1926">{{cite journal | vauthors=Kötz A, Merkel P |date=May 1926 |title=Zur Kenntnis hydroaromatischer Alkamine |journal=Journal für Praktische Chemie |language=de |volume=113 |issue=1 |pages=49–76 |doi=10.1002/prac.19261130107 |issn=0021-8383}}</ref>

It was again synthesized in 1956 by chemist H Victor Maddox and brought to market as an [[anesthetic]] medication by pharmaceutical company Parke-Davis, now a subsidiary of [[Pfizer]].<ref name="Lodge_2015" /><ref name="Zed2007" /><ref>{{cite book |url=https://books.google.com/books?id=tX7nCAAAQBAJ&pg=PA717|title=Neuropsychopharmacology: Proceedings of the XVIth C.I.N.P. Congress, Munich, August, 15-19, 1988|vauthors=Bunney Jr WE, Hippius H, Laakmann G, Schmauß M|date=2012|publisher=Springer Science & Business Media |isbn=978-3-642-74034-3 |page=717 |via=Google Books}}</ref><ref name="Kötz_1926" /><ref name="Lindgren 1983 61–73">{{cite book|vauthors=Lindgren JE, Holmstedt B|title=Toxicology in the Use, Misuse, and Abuse of Food, Drugs, and Chemicals |series= Archives of Toxicology | publisher=Springer Berlin Heidelberg| year= 1983 |isbn= 978-3-540-12392-7|volume=6|location=Berlin, Heidelberg|pages=61–73| chapter= Guide to the Analysis of Phencyclidine and its Metabolites in Biological Material| doi= 10.1007/978-3-642-69083-9_10|issn=0171-9750|pmid=6578750}}</ref> Its use in humans was disallowed in the US in 1965 due to the high rates of [[side effects]], while its use in animals was disallowed in 1978.<ref name="Jus2003" /><ref name= "Zed2007" /><ref name="Tas2015">{{cite book| url= https://books.google.com/books?id=l2KRBgAAQBAJ&pg=PT4843 |title= Psychiatry, 2 Volume Set|vauthors=Tasman A, Kay J, Lieberman JA, First MB, Riba M |year= 2015| publisher= John Wiley & Sons|isbn=978-1-118-75336-1 |page=4943 | via= Google Books}}</ref> Moreover, [[ketamine]] was discovered and was better tolerated as an anesthetic.<ref name="Tas2015" /> 

PCP is classified as a [[schedule II drug]] in the US.<ref name= "Jus2003" /> Derivatives of PCP have been sold for recreational and non-medical use.<ref name= "Morris2014" />