Editing Pancreas (section)

===Inflammation===
{{Main|Pancreatitis}}
Inflammation of the pancreas is known as [[pancreatitis]]. Pancreatitis is most often associated with recurrent [[gallstone]]s or chronic alcohol use, with other common causes including traumatic damage, damage following an [[ERCP]], some medications, infections such as [[mumps]] and [[hypertriglyceridaemia|very high blood triglyceride levels]]. Acute pancreatitis is likely to cause intense pain in the central [[abdomen]], that often radiates to the back, and may be associated with nausea or vomiting. Severe pancreatitis may lead to bleeding or perforation of the pancreas resulting in [[shock (circulatory)|shock]] or a [[systemic inflammatory response syndrome]], [[Grey Turner's sign|bruising of the flanks]] or the [[Cullen's sign|region around the belly button]]. These severe complications are often managed in an [[intensive care unit]].{{sfn|Davidson's|2018|p=837-844}}

In pancreatitis, enzymes of the exocrine pancreas damage the structure and tissue of the pancreas. Detection of some of these enzymes, such as [[amylase]] and [[lipase]] in the blood, along with symptoms and findings on [[medical imaging]] such as [[ultrasound]] or a [[CT scan]], are often used to indicate that a person has pancreatitis. Pancreatitis is often managed medically with [[analgesic|pain relief]], and monitoring to prevent or manage shock, and management of any identified underlying causes. This may include removal of gallstones, lowering of blood triglyceride or glucose levels, the use of [[corticosteroid]]s for [[autoimmune pancreatitis]], and the cessation of any medication triggers.{{sfn|Davidson's|2018|p=837-844}}

[[Chronic pancreatitis]] refers to the development of pancreatitis over time. It shares many similar causes, with the most common being chronic alcohol use, with other causes including recurrent acute episodes and [[cystic fibrosis]]. Abdominal pain, characteristically relieved by sitting forward or drinking alcohol, is the most common symptom. When the digestive function of the pancreas is severely affected, this may lead to problems with fat digestion and the development of [[steatorrhoea]]; when the endocrine function is affected, this may lead to diabetes. Chronic pancreatitis is investigated in a similar way to acute pancreatitis. In addition to management of pain and nausea, and management of any identified causes (which may include [[alcohol cessation]]), because of the digestive role of the pancreas, [[enzyme replacement]] may be needed to prevent [[malabsorption]].{{sfn|Davidson's|2018|p=837-844}}