Editing Morphine (section)

== Toxicity ==
{{See also|Opioid overdose}}
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! {{Chemical datatable header}} | Properties of Morphine
|-
| [[Molar mass]]<ref name="CRC_85">{{cite book | veditors = Lide DR |title = CRC handbook of chemistry and physics: a ready-reference book of chemical and physical data |year = 2004 |edition = 85 |publisher = CRC Press |location = Boca Ratan Florida |isbn = 978-0-8493-0485-9 |url = https://archive.org/details/crchandbookofche81lide }}</ref>
| 285.338 g/mol
|-
| [[Acidity]] (p''K''<sub>a</sub>)<ref name="CRC_85" />
|
{|
| Step 1: 8.21 || at 25&nbsp;°C
|-
| Step 2: 9.85 || at 20&nbsp;°C
|}
|-
| [[Solubility]]<ref name="CRC_85" />
| 0.15 g/L at 20&nbsp;°C
|-
| [[Melting point]]<ref name="CRC_85" />
| 255&nbsp;°C
|-
| [[Boiling point]]<ref name="CRC_85" />
| 190&nbsp;°C sublimes
|-
|}

A large [[overdose]] can cause [[asphyxia]] and death by respiratory depression if the person does not receive medical attention immediately.<ref name=Duldner>{{cite web | url = https://www.nlm.nih.gov/medlineplus/ency/article/002502.htm | work = MedlinePlus | publisher = U.S. National Library of Medicine | title = Morphine overdose | archive-url = https://web.archive.org/web/20160524084700/https://www.nlm.nih.gov/medlineplus/ency/article/002502.htm | archive-date= 24 May 2016 | date = 2 March 2009 | vauthors = Duldner Jr JE }}</ref> Overdose treatment includes the administration of [[naloxone]]. The latter completely reverses morphine's effects but may result in the immediate onset of withdrawal in opiate-addicted subjects. Multiple doses may be needed as the duration of action of morphine is longer than that of naloxone.<ref>{{cite journal | vauthors = Boyer EW | title = Management of opioid analgesic overdose | journal = The New England Journal of Medicine | volume = 367 | issue = 2 | pages = 146–155 | date = July 2012 | pmid = 22784117 | pmc = 3739053 | doi = 10.1056/NEJMra1202561 }}</ref>