Editing Molecular evolution (section)

==Constructive neutral evolution==
{{Main|Constructive neutral evolution}}

[[Constructive neutral evolution]] (CNE) explains that complex systems can emerge and spread into a population through neutral transitions with the principles of excess capacity, presuppression, and ratcheting,<ref>{{cite journal | vauthors = Stoltzfus A | title = On the possibility of constructive neutral evolution | journal = Journal of Molecular Evolution | volume = 49 | issue = 2 | pages = 169–181 | date = August 1999 | pmid = 10441669 | doi = 10.1007/PL00006540 | bibcode = 1999JMolE..49..169S | s2cid = 1743092 }}</ref><ref>{{cite journal | vauthors = Stoltzfus A | title = Constructive neutral evolution: exploring evolutionary theory's curious disconnect | journal = Biology Direct | volume = 7 | issue = 1 | pages = 35 | date = October 2012 | pmid = 23062217 | pmc = 3534586 | doi = 10.1186/1745-6150-7-35 | doi-access = free }}</ref><ref>{{cite journal | vauthors = Muñoz-Gómez SA, Bilolikar G, Wideman JG, Geiler-Samerotte K | title = Constructive Neutral Evolution 20 Years Later | journal = Journal of Molecular Evolution | volume = 89 | issue = 3 | pages = 172–182 | date = April 2021 | pmid = 33604782 | pmc = 7982386 | doi = 10.1007/s00239-021-09996-y | bibcode = 2021JMolE..89..172M }}</ref> and it has been applied in areas ranging from the origins of the [[spliceosome]] to the complex interdependence of [[Microbial consortium|microbial communities]].<ref>{{cite journal | vauthors = Lukeš J, Archibald JM, Keeling PJ, Doolittle WF, Gray MW | title = How a neutral evolutionary ratchet can build cellular complexity | journal = IUBMB Life | volume = 63 | issue = 7 | pages = 528–537 | date = July 2011 | pmid = 21698757 | doi = 10.1002/iub.489 | s2cid = 7306575 }}</ref><ref>{{cite journal | vauthors = Vosseberg J, Snel B | title = Domestication of self-splicing introns during eukaryogenesis: the rise of the complex spliceosomal machinery | journal = Biology Direct | volume = 12 | issue = 1 | pages = 30 | date = December 2017 | pmid = 29191215 | pmc = 5709842 | doi = 10.1186/s13062-017-0201-6 | doi-access = free }}</ref><ref>{{Cite journal | vauthors = Brunet TD, Doolittle WF |date=19 March 2018 |title=The generality of Constructive Neutral Evolution |journal=Biology & Philosophy |language=en |volume=33 |issue=1 |pages=2 |doi=10.1007/s10539-018-9614-6 |issn=1572-8404 |s2cid=90290787|url=https://www.repository.cam.ac.uk/handle/1810/278897 }}</ref>