Editing Metastasis (section)

==History==
The first physician to report the possibility of local metastasis from a primary cancerous source to nearby tissues was [[Avicenna|Ibn Sina]]. He described a case of breast cancer and metastatic condition in [[The Canon of Medicine]]. His hypothesis was based on clinical course of the patient.<ref>{{Cite journal |vauthors=Zarshenas MM, Mohammadi-Bardbori A |date=February 2017 |title=A medieval description of metastatic breast cancer; from Avicenna's view point |journal=Breast |volume=31 |pages=20–21 |doi=10.1016/j.breast.2016.10.019 |pmid=27810694}}</ref><ref>{{Cite journal |vauthors=Kardeh S, Kardeh B |date=2019-01-01 |title=Avicenna's Concepts on Cancer Metastasis from the 11th Century |journal=Galen Medical Journal |volume=8 |pages=e1292 |doi=10.31661/gmj.v8i0.1292 |doi-broken-date=1 November 2024 |pmc=8344088 |pmid=34466487}}</ref>

In March 2014 researchers discovered the oldest complete example of a human with metastatic cancer. The tumors had developed in a 3,000-year-old skeleton found in 2013 in a tomb in [[Sudan]] dating back to 1200 BC. The skeleton was analyzed using radiography and a scanning electron microscope. These findings were published in the ''[[Public Library of Science]]'' journal.<ref name="Kelland-cancer">{{Cite news |date=17 March 2014 |title=Archaeologists discover earliest example of human with cancer |url=https://www.reuters.com/article/us-cancer-ancient-idUSBREA2G1BL20140317 |access-date=18 March 2014 |work=Reuters |vauthors=Kelland K}}</ref><ref name="Ghosh-cancer">{{Cite news |date=18 March 2014 |title=Ancient skeleton is the earliest case of cancer yet detected |url=https://www.bbc.com/news/science-environment-26627941 |access-date=18 March 2014 |work=BBC |vauthors=Ghosh P}}</ref><ref name="Ross-cancer">{{Cite news |date=17 March 2014 |title=Possible Oldest Cancer Found In 3,000-Year-Old Skeleton Could Reveal 'Evolution' Of Modern Disease |url=http://www.ibtimes.com/possible-oldest-cancer-found-3000-year-old-skeleton-could-reveal-evolution-modern-disease-1561953 |access-date=18 March 2014 |work=International Business Times |vauthors=Ross P}}</ref>