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==Prognosis== Like most aspects of the disorder, [[life expectancy]] varies with severity and adequate treatment. People with severe haemophilia who do not receive adequate, modern treatment have greatly shortened lifespans and often do not reach maturity. Prior to the 1960s when effective treatment became available, average life expectancy was only 11 years.<ref name=emed>[http://emedicine.medscape.com/article/210104-overview Hemophilia Overview] {{webarchive|url=https://web.archive.org/web/20090927063244/http://emedicine.medscape.com/article/210104-overview |date=27 September 2009 }} eMedicine from webMD. Dimitrios P Agaliotis, MD, PhD, FACP, Robert A Zaiden, MD, Fellow, and Saduman Ozturk, PA-C. Updated: 24 November 2009.</ref> By the 1980s the life span of the average haemophiliac receiving appropriate treatment was 50β60 years.<ref name=emed/> Today with appropriate treatment, males with haemophilia typically have a near normal [[quality of life]] with an average lifespan approximately 10 years shorter than an unaffected male.<ref>[http://www.wfh.org/en/page.aspx?pid=637#Life_expectancy World Federation of Hemophilia] {{webarchive|url=https://web.archive.org/web/20140201162113/http://www.wfh.org/en/page.aspx?pid=637 |date=1 February 2014 }} Frequently Asked Questions. 2005</ref> Since the 1980s the primary leading cause of death of people with severe haemophilia has shifted from [[bleeding|haemorrhage]] to HIV/AIDS acquired through treatment with [[blood donation restrictions on men who have sex with men|contaminated blood products]].<ref name=emed/> The second leading cause of death related to severe haemophilia complications is intracranial haemorrhage which today accounts for one third of all deaths of people with haemophilia. Two other major causes of death include [[hepatitis]] infections causing [[cirrhosis]] and obstruction of air or blood flow due to soft tissue haemorrhage.<ref name=emed/>
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