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== Prognosis == [[File:Pertussis world map - DALY - WHO2004.svg|thumb|upright=1.3|[[Disability-adjusted life year]] for pertussis per 100,000 inhabitants as of 2004.{{Div col|small=yes|colwidth=10em}} {{legend|#b3b3b3|No data}} {{legend|#ffff65|Less than 50}} {{legend|#fff200|50β100}} {{legend|#ffdc00|100β150}} {{legend|#ffc600|150β200}} {{legend|#ffb000|200β250}} {{legend|#ff9a00|250β300}} {{legend|#ff8400|300β350}} {{legend|#ff6e00|350β400}} {{legend|#ff5800|400β450}} {{legend|#ff4200|450β500}} {{legend|#ff2c00|500β550}} {{legend|#cb0000|More than 550}} {{div col end}}]] While most healthy older children and adults fully recover, infection in newborns is particularly severe. Pertussis is fatal in an estimated 0.5% of US infants under one year of age.<ref name="complications">{{cite web |title=Pertussis: Complications |url=https://www.cdc.gov/pertussis/about/complications.html |publisher=[[Centers for Disease Control and Prevention]] |access-date=24 August 2012 |url-status=live |archive-url=https://web.archive.org/web/20120814112442/http://www.cdc.gov/pertussis/about/complications.html |archive-date=14 August 2012 }}</ref> First-year infants are also more likely to develop complications, such as [[apnea]]s (31%), pneumonia (12%), seizures (0.6%) and [[encephalopathy]] (0.15%).<ref name="complications"/> This may be due to the ability of the bacterium to suppress the [[immune system]].<ref>{{cite journal | vauthors = Carbonetti NH | title = Pertussis toxin and adenylate cyclase toxin: key virulence factors of Bordetella pertussis and cell biology tools | journal = Future Microbiology | volume = 5 | issue = 3 | pages = 455β69 | date = March 2010 | pmid = 20210554 | pmc = 2851156 | doi = 10.2217/fmb.09.133 }}</ref>
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