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===Cancer=== Several meta-analyses have found no increased risk of cancer, and some meta-analyses have found a reduced risk.<ref>{{cite journal | vauthors = Jukema JW, Cannon CP, de Craen AJ, Westendorp RG, Trompet S | title = The controversies of statin therapy: weighing the evidence | journal = Journal of the American College of Cardiology | volume = 60 | issue = 10 | pages = 875β881 | date = September 2012 | pmid = 22902202 | doi = 10.1016/j.jacc.2012.07.007 | doi-access = free | title-link = doi }}</ref><ref>{{cite journal | vauthors = Rutishauser J | title = Statins in clinical medicine | journal = [[Swiss Medical Weekly]] | volume = 141 | pages = w13310 | date = 21 November 2011 | pmid = 22101921 | doi = 10.4414/smw.2011.13310 | doi-access = free | title-link = doi }}</ref><ref>{{cite journal | vauthors = Alsheikh-Ali AA, Maddukuri PV, Han H, Karas RH | title = Effect of the magnitude of lipid lowering on risk of elevated liver enzymes, rhabdomyolysis, and cancer: insights from large randomized statin trials | journal = Journal of the American College of Cardiology | volume = 50 | issue = 5 | pages = 409β418 | date = July 2007 | pmid = 17662392 | doi = 10.1016/j.jacc.2007.02.073 | doi-access = free | title-link = doi }}</ref><ref name="Dale2006">{{cite journal | vauthors = Dale KM, Coleman CI, Henyan NN, Kluger J, White CM | title = Statins and cancer risk: a meta-analysis | journal = JAMA | volume = 295 | issue = 1 | pages = 74β80 | date = January 2006 | pmid = 16391219 | doi = 10.1001/jama.295.1.74 }}</ref><ref>{{cite journal | vauthors = Alsheikh-Ali AA, Karas RH | title = The relationship of statins to rhabdomyolysis, malignancy, and hepatic toxicity: evidence from clinical trials | journal = Current Atherosclerosis Reports | volume = 11 | issue = 2 | pages = 100β104 | date = March 2009 | pmid = 19228482 | doi = 10.1007/s11883-009-0016-8 | s2cid = 42869773 }}</ref> Specifically, statins may reduce the risk of [[esophageal cancer]],<ref>{{cite journal | vauthors = Singh S, Singh AG, Singh PP, Murad MH, Iyer PG | title = Statins are associated with reduced risk of esophageal cancer, particularly in patients with Barrett's esophagus: a systematic review and meta-analysis | journal = Clinical Gastroenterology and Hepatology | volume = 11 | issue = 6 | pages = 620β629 | date = June 2013 | pmid = 23357487 | pmc = 3660516 | doi = 10.1016/j.cgh.2012.12.036 }}</ref> [[colorectal cancer]],<ref>{{cite journal | vauthors = Liu Y, Tang W, Wang J, Xie L, Li T, He Y, Deng Y, Peng Q, Li S, Qin X | title = Association between statin use and colorectal cancer risk: a meta-analysis of 42 studies | journal = Cancer Causes & Control | volume = 25 | issue = 2 | pages = 237β249 | date = February 2014 | pmid = 24265089 | doi = 10.1007/s10552-013-0326-6 | s2cid = 17931279 }}</ref> [[gastric cancer]],<ref>{{cite journal | vauthors = Wu XD, Zeng K, Xue FQ, Chen JH, Chen YQ | title = Statins are associated with reduced risk of gastric cancer: a meta-analysis | journal = European Journal of Clinical Pharmacology | volume = 69 | issue = 10 | pages = 1855β1860 | date = October 2013 | pmid = 23748751 | doi = 10.1007/s00228-013-1547-z | s2cid = 16584300 }}</ref><ref>{{cite journal | vauthors = Singh PP, Singh S | title = Statins are associated with reduced risk of gastric cancer: a systematic review and meta-analysis | journal = Annals of Oncology | volume = 24 | issue = 7 | pages = 1721β1730 | date = July 2013 | pmid = 23599253 | doi = 10.1093/annonc/mdt150 | doi-access = free | title-link = doi }}</ref> [[hepatocellular carcinoma]],<ref>{{cite journal | vauthors = Pradelli D, Soranna D, Scotti L, Zambon A, Catapano A, Mancia G, La Vecchia C, Corrao G | title = Statins and primary liver cancer: a meta-analysis of observational studies | journal = European Journal of Cancer Prevention | volume = 22 | issue = 3 | pages = 229β234 | date = May 2013 | pmid = 23010949 | doi = 10.1097/cej.0b013e328358761a | s2cid = 37195287 }}</ref> and possibly [[prostate cancer]].<ref>{{cite journal | vauthors = Zhang Y, Zang T | title = Association between statin usage and prostate cancer prevention: a refined meta-analysis based on literature from the years 2005-2010 | journal = Urologia Internationalis | volume = 90 | issue = 3 | pages = 259β262 | year = 2013 | pmid = 23052323 | doi = 10.1159/000341977 | s2cid = 22078921 }}</ref><ref>{{cite journal | vauthors = Bansal D, Undela K, D'Cruz S, Schifano F | title = Statin use and risk of prostate cancer: a meta-analysis of observational studies | journal = PLOS ONE | volume = 7 | issue = 10 | pages = e46691 | year = 2012 | pmid = 23049713 | pmc = 3462187 | doi = 10.1371/journal.pone.0046691 | bibcode = 2012PLoSO...746691B | doi-access = free | title-link = doi }}</ref> They appear to have no effect on the risk of [[lung cancer]],<ref>{{cite journal | vauthors = Tan M, Song X, Zhang G, Peng A, Li X, Li M, Liu Y, Wang C | title = Statins and the risk of lung cancer: a meta-analysis | journal = PLOS ONE | volume = 8 | issue = 2 | pages = e57349 | year = 2013 | pmid = 23468972 | pmc = 3585354 | doi = 10.1371/journal.pone.0057349 | bibcode = 2013PLoSO...857349T | doi-access = free | title-link = doi }}</ref> [[kidney cancer]],<ref>{{cite journal | vauthors = Zhang XL, Liu M, Qian J, Zheng JH, Zhang XP, Guo CC, Geng J, Peng B, Che JP, Wu Y | title = Statin use and risk of kidney cancer: a meta-analysis of observational studies and randomized trials | journal = British Journal of Clinical Pharmacology | volume = 77 | issue = 3 | pages = 458β465 | date = March 2014 | pmid = 23879311 | pmc = 3952720 | doi = 10.1111/bcp.12210 }}</ref> [[breast cancer]],<ref>{{cite journal | vauthors = Undela K, Srikanth V, Bansal D | title = Statin use and risk of breast cancer: a meta-analysis of observational studies | journal = Breast Cancer Research and Treatment | volume = 135 | issue = 1 | pages = 261β269 | date = August 2012 | pmid = 22806241 | doi = 10.1007/s10549-012-2154-x | s2cid = 35249884 }}</ref> [[pancreatic cancer]],<ref>{{cite journal | vauthors = Cui X, Xie Y, Chen M, Li J, Liao X, Shen J, Shi M, Li W, Zheng H, Jiang B | title = Statin use and risk of pancreatic cancer: a meta-analysis | journal = Cancer Causes & Control | volume = 23 | issue = 7 | pages = 1099β1111 | date = July 2012 | pmid = 22562222 | doi = 10.1007/s10552-012-9979-9 | s2cid = 13171692 }}</ref> or [[bladder cancer]].<ref>{{cite journal | vauthors = Zhang XL, Geng J, Zhang XP, Peng B, Che JP, Yan Y, Wang GC, Xia SQ, Wu Y, Zheng JH | title = Statin use and risk of bladder cancer: a meta-analysis | journal = Cancer Causes & Control | volume = 24 | issue = 4 | pages = 769β776 | date = April 2013 | pmid = 23361339 | doi = 10.1007/s10552-013-0159-3 | s2cid = 9030195 }}</ref>
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