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===Habitability=== {{main|Effect of spaceflight on the human body}} The space station environment presents a variety of challenges to human habitability, including short-term problems such as the limited supplies of air, water, and food and the need to manage [[waste heat]], and long-term ones such as [[weightlessness]] and relatively high levels of [[ionizing radiation]]. These conditions can create long-term health problems for space-station inhabitants, including [[muscle atrophy]], [[Spaceflight osteopenia|bone deterioration]], [[Space adaptation syndrome|balance disorders]], [[Visual impairment due to intracranial pressure|eyesight disorders]], and elevated risk of [[cancer]].<ref name="NYT-20140127">{{cite news |last=Chang |first=Kenneth |date=27 January 2014 |title=Beings Not Made for Space |work=[[New York Times]] |url=https://www.nytimes.com/2014/01/28/science/bodies-not-made-for-space.html |access-date=27 January 2014}}</ref> Future [[space habitat]]s may attempt to address these issues, and could be designed for occupation beyond the weeks or months that current missions typically last. Possible solutions include the creation of [[artificial gravity]] by a [[Rotating wheel space station|rotating structure]], the inclusion of [[radiation shielding]], and the development of on-site agricultural ecosystems. Some designs might even accommodate large numbers of people, becoming essentially "cities in space" where people would reside semi-permanently.<ref>{{Cite web |year=1975 |title=Space Settlements: A Design Study |url=https://settlement.arc.nasa.gov/75SummerStudy/s.s.doc.html |url-status=dead |archive-url=https://web.archive.org/web/20100531200344/http://settlement.arc.nasa.gov/75SummerStudy/s.s.doc.html |archive-date=31 May 2010 |access-date=10 February 2018 |publisher=[[NASA]]}}</ref> Molds that develop aboard space stations can produce acids that degrade metal, glass, and rubber. Despite an expanding array of molecular approaches for detecting microorganisms, rapid and robust means of assessing the differential viability of the microbial cells, as a function of phylogenetic lineage, remain elusive.<ref>{{cite web |first=Trudy E. |last=Bell |year=2007 |title=Preventing "Sick" Spaceships |url=https://science.nasa.gov/science-news/science-at-nasa/2007/11may_locad3/ |access-date=2017-07-12 |archive-date=2017-05-14 |archive-url=https://web.archive.org/web/20170514233537/https://science.nasa.gov/science-news/science-at-nasa/2007/11may_locad3 |url-status=dead }}</ref>
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