Editing Protein production (section)

===== Mammalian systems =====
The most common mammalian expression systems are [[Chinese hamster|Chinese Hamster]] [[ovary]] (CHO) and Human embryonic kidney (HEK) cells.<ref name="Zhu 1158–1170">{{cite journal | vauthors = Zhu J | title = Mammalian cell protein expression for biopharmaceutical production | journal = Biotechnology Advances | volume = 30 | issue = 5 | pages = 1158–70 | date = 2012-09-01 | pmid = 21968146 | doi = 10.1016/j.biotechadv.2011.08.022 }}</ref><ref name=":0">{{cite journal | vauthors = Almo SC, Love JD | title = Better and faster: improvements and optimization for mammalian recombinant protein production | journal = Current Opinion in Structural Biology | volume = 26 | pages = 39–43 | date = June 2014 | pmid = 24721463 | pmc = 4766836 | doi = 10.1016/j.sbi.2014.03.006 | series = New constructs and expression of proteins / Sequences and topology }}</ref><ref>{{cite journal | vauthors = Hacker DL, Balasubramanian S | title = Recombinant protein production from stable mammalian cell lines and pools | journal = Current Opinion in Structural Biology | volume = 38 | pages = 129–36 | date = June 2016 | pmid = 27322762 | doi = 10.1016/j.sbi.2016.06.005 | series = New constructs and expression of proteins • Sequences and topology }}</ref>
* [[Chinese hamster ovary cell]]<ref name=":0" />
* [[Mouse]] myeloma [[Lymphoblast|lymphoblstoid]] (e.g. NS0 cell)<ref name="Zhu 1158–1170"/>
* Fully Human
** Human embryonic kidney cells ([[HEK 293 cells|HEK-293]])<ref name=":0" />
** Human embryonic retinal cells (Crucell's Per.C6)<ref name=":0" />
** Human [[amniocyte]] cells (Glycotope and CEVEC){{Cn|date=January 2024}}