Editing Phencyclidine (section)

===Analogues===
[[File:ACHA SAR.png|class=skin-invert-image|210px|right|thumbnail|Possible analogues of PCP]]
Fewer than 30 different [[structural analog|analogs]] of PCP were reported as being used as a [[street drug]] during the 1970s and 1980s, mainly in the United States.<ref name="Morris2014" /> Only a few of these compounds were widely used, including [[rolicyclidine]] (PCPy), [[eticyclidine]] (PCE), and [[tenocyclidine]] (TCP).<ref name="Morris2014" /> Less common analogs include [[3-HO-PCP]], [[3-MeO-PCMo]], and [[3-MeO-PCP]].

The generalized structural motif required for PCP-like activity is derived from structure-activity relationship studies of PCP derivatives. All of these derivatives are likely to share some of their psychoactive effects with PCP itself, although a range of potencies and varying mixtures of anesthetic, dissociative, and stimulant effects are known, depending on the particular drug and its substituents. In the United States, all of these compounds would be considered controlled substance analogs of PCP under the [[Federal Analog Act]] and are hence illegal drugs if sold for human consumption.<ref>{{cite journal | vauthors = Itzhak Y, Kalir A, Weissman BA, Cohen S | title = New analgesic drugs derived from phencyclidine | journal = Journal of Medicinal Chemistry | volume = 24 | issue = 5 | pages = 496–9 | date = May 1981 | pmid = 7241506 | doi = 10.1021/jm00137a004 }}</ref><ref>{{cite journal | vauthors = Chaudieu I, Vignon J, Chicheportiche M, Kamenka JM, Trouiller G, Chicheportiche R | title = Role of the aromatic group in the inhibition of phencyclidine binding and dopamine uptake by PCP analogs | journal = Pharmacology Biochemistry and Behavior | volume = 32 | issue = 3 | pages = 699–705 | date = Mar 1989 | pmid = 2544905 | doi = 10.1016/0091-3057(89)90020-8 | s2cid = 7672918 }}</ref>