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=== Early Symptoms === Early symptoms that require investigation include symptoms from multiple sclerosis (twitching, lack of coordination, slurred speech, frequent episodes of partial vision loss or blurred vision), episodes of "disturbed/blackened" rather than blurry indicate moderate stage and require immediate medical attention to prevent further loss of vision. Other early symptoms are reduced [[night vision]], [[photophobia]] and [[Red eye (medicine)|red eyes]]. ====Variation in symptoms with age==== Several case studies in children have demonstrated the absence of pain in more than half of cases (approximately 60%) in their pediatric study population, with the most common symptom reported simply as "blurriness".<ref>{{cite journal |vauthors=Lucchinetti CF, Kiers L, O'Duffy A, Gomez MR, Cross S, Leavitt JA, O'Brien P, Rodriguez M |date=November 1997 |title=Risk factors for developing multiple sclerosis after childhood optic neuritis |journal=Neurology |volume=49 |issue=5 |pages=1413β1418 |doi=10.1212/WNL.49.5.1413 |pmid=9371931 |s2cid=33205877}}</ref><ref>{{cite journal |vauthors=Lana-Peixoto MA, Andrade GC |date=June 2001 |title=The clinical profile of childhood optic neuritis |journal=Arquivos de Neuro-Psiquiatria |volume=59 |issue=2βB |pages=311β317 |doi=10.1590/S0004-282X2001000300001 |pmid=11460171 |doi-access=free}}</ref> Other remarkable differences between the presentation of adult optic neuritis as compared to pediatric cases include more often unilateral optic neuritis in adults, while children much predominantly present with bilateral involvement.
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