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===Evolutionary biology=== By combining microfluidics with [[landscape ecology]] and [[nanofluidics]], a nano/micro fabricated fluidic landscape can be constructed by building local patches of [[bacterial]] [[habitat]] and connecting them by dispersal corridors. The resulting landscapes can be used as physical implementations of an [[adaptive landscape]],<ref>{{cite journal | vauthors = Keymer JE, Galajda P, Muldoon C, Park S, Austin RH | title = Bacterial metapopulations in nanofabricated landscapes | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 103 | issue = 46 | pages = 17290β17295 | date = November 2006 | pmid = 17090676 | pmc = 1635019 | doi = 10.1073/pnas.0607971103 | doi-access = free | bibcode = 2006PNAS..10317290K }}</ref> by generating a spatial mosaic of patches of opportunity distributed in space and time. The patchy nature of these fluidic landscapes allows for the study of adapting bacterial cells in a [[metapopulation]] system. The [[evolutionary ecology]] of these bacterial systems in these [[synthetic ecosystems]] allows for using [[biophysics]] to address questions in [[evolutionary biology]].
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