Editing Magnolia (section)

=== Chemical compounds and bioeffects ===
The aromatic bark contains [[magnolol]], [[honokiol]], [[4-O-methylhonokiol]], and [[obovatol]].<ref>{{cite journal |author1=Han, H. |author2=Jung, J.K. |author3=Han, S.B. |author4=Nam, S.Y. |author5=Oh, K.W. |author6=Hong, J.T. |title=Anxiolytic-like effects of 4-O-methylhonokiol isolated from magnolia officinalis through enhancement of GABAergic transmission and chloride influx |journal=Journal of Medicinal Food |volume=14 |issue=7–8 |pages=724–731 |year=2011 |doi=10.1089/jmf.2010.1111 |pmid=21501091}}</ref><ref>{{cite journal |author1=Kalman, D.S. |author2=Feldman, S. |author3=Feldman, R. |author4=Schwartz, H.I. |author5=Krieger, D.R. |author6=Garrison, R. |title=Effect of a proprietary Magnolia and Phellodendron extract on stress levels in healthy women: A pilot, double-blind, placebo-controlled clinical trial |journal=Nutrition Journal |volume=7 |issue=1 |year=2008 |doi=10.1186/1475-2891-7-11 |pmid=18426577 |pmc=2359758 |pages=11 |doi-access=free }}</ref><ref>{{cite journal |author1=Ma, L. |author2=Chen, J. |author3=Wang, X. |author4=Liang, X. |author5=Luo, Y. |author6=Zhu, W. |author7=Wang, T. |author8=Peng, M. |author9=Li, S. |author10=Jie, S. |author11=Peng, A. |author12=Wei, Y. |author13=Chen, L. |title=Structural modification of honokiol, a biphenyl occurring in magnolia officinalis: The evaluation of honokiol analogues as inhibitors of angiogenesis and for their cytotoxicity and structure-activity relationship |journal=Journal of Medicinal Chemistry |volume=54 |issue=19 |pages=6469–6481 |year=2011 |doi=10.1021/jm200830u |pmid=21853991}}</ref><ref>{{cite journal |author1=Fried, L.E. |author2=Arbiser, J.L. |title=Honokiol, a multifunctional antiangiogenic and antitumor agent |journal=Antioxidants & Redox Signaling |volume=11 |pages=1139–1148 |year=2009 |issue=5 |doi=10.1089/ars.2009.2440 |pmid=19203212 |pmc=2842137}}</ref><ref>{{cite journal |author1=Hu J. |author2=Chen L.-J. |author3=Liu L. |author4=Chen X. |author5=Chen P. |author6=Yang G.-L. |author7=Hou W.-L. |author8=Tang M.-H. |author9=Zhang F. |author10=Wang X.-H. |author11=Zhao X. |author12=Wei Y.-Q. |title=Liposomal honokiol, a potent anti-angiogenesis agent, in combination with radiotherapy produces a synergistic antitumor efficacy without increasing toxicity |journal=[[Experimental & Molecular Medicine]] |volume=40 |issue=6 |pages=617–628 |year=2008 |doi=10.3858/emm.2008.40.6.617 |pmid=19116447 |pmc=2679338}}</ref><ref>{{cite journal |vauthors=Lee YJ, Lee YM, Lee CK, Jung JK, Han SB, Hong JT |title=Therapeutic applications of compounds in the Magnolia family |journal=Pharmacol. Ther. |year=2011 |volume=130 |issue=2 |pages=157–176 |doi=10.1016/j.pharmthera.2011.01.010 |pmid=21277893}}</ref> Magnolol<ref>{{cite journal |last1=Fakhrudin |first1=N. |last2=Ladurner |first2=A. |last3=Atanasov |first3=A.G. |last4=Heiss |first4=E.H. |last5=Baumgartner |first5=L. |last6=Markt |first6=P. |last7=Schuster |first7=D. |last8=Ellmerer |first8=E.P. |last9=Wolber |first9=G. |last10=Rollinger |first10=J.M. |last11=Stuppner |first11=H. |last12=Dirsch |first12=V.M. |date=Apr 2010 |title=Computer-aided discovery, validation, and mechanistic characterization of novel neolignan activators of peroxisome proliferator-activated receptor gamma |journal=Mol. Pharmacol. |volume=77 |issue=4 |pages=559–66 |doi=10.1124/mol.109.062141 |pmid=20064974 |pmc=3523390}}</ref> and honokiol<ref>{{cite journal |vauthors=Atanasov AG, Wang JN, Gu SP, Bu J, Kramer MP, Baumgartner L, Fakhrudin N, Ladurner A, Malainer C, Vuorinen A, Noha SM, Schwaiger S, Rollinger JM, Schuster D, Stuppner H, Dirsch VM, Heiss EH |title=Honokiol: A non-adipogenic PPARγ agonist from nature |pmid=23811337 |doi=10.1016/j.bbagen.2013.06.021 |volume=1830 |issue=10 |pmc=3790966 |date=October 2013 |pages=4813–4819 |journal=Biochimica et Biophysica Acta (BBA) - General Subjects}}</ref> activate the [[nuclear receptor]] [[peroxisome proliferator-activated receptor gamma]].