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===Origins and Controversy=== Chi-An Cheng at National Taiwan University (NTU) has claimed that her team developed this innovative technology.<ref>{{cite web |last1=Cheng |first1=CA |title=eSimoa β ultrasensitive and high-resolution protein spatially decoding framework for tumor extracellular vesicles {{!}} Exosome RNA |url=https://exosome-rna.com/esimoa-ultrasensitive-and-high-resolution-protein-spatially-decoding-framework-for-tumor-extracellular-vesicles/ |website=Exosome RNA |date=28 November 2023}}</ref><ref>{{cite journal |last1=Cheng |first1=Chi-An |title=Voices in Molecular Pharmaceutics: Meet Professor Chi-An Cheng, Who Is Innovating Diagnostic Tools, Discovering Biomarkers, Developing New Assays, and Creating New Materials |journal=Molecular Pharmaceutics |language=en |doi=10.1021/acs.molpharmaceut.4c00623 |date=13 June 2024|volume=21 |issue=7 |pages=3082β3083 |pmid=38869420 |doi-access=free }}</ref> However, this claim is contested by the existence of prior publications by David R. Walt's team at Harvard University, who published their work on eSimoa in 2020.<ref name="Ultrasensitive Detection of Enzymat"/><ref>{{cite web |title=Detection of Other Biomolecules β Walt Lab |url=https://waltlab.bwh.harvard.edu/research/new-technology/ultrasensitive-detection-of-small-molecules/|website=Brigham and Womenβs Hospital|access-date=10 April 2025}}</ref> This earlier documentation by Walt's team suggests a prior contribution to the development of the technology.
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