Editing Chemotherapy (section)

=== Neutropenic enterocolitis ===
Due to immune system suppression, [[neutropenic enterocolitis]] (typhlitis) is a "life-threatening gastrointestinal complication of chemotherapy."<ref>{{cite journal | vauthors = Davila ML | title = Neutropenic enterocolitis | journal = Current Opinion in Gastroenterology | volume = 22 | issue = 1 | pages = 44–7 | date = January 2006 | pmid = 16319675 | doi = 10.1097/01.mog.0000198073.14169.3b | doi-broken-date = 5 April 2025 | s2cid = 25479771 }}</ref> [[Typhlitis]] is an intestinal infection which may manifest itself through symptoms including [[nausea]], [[vomiting]], [[diarrhea]], a [[distended abdomen]], [[fever]], [[chills]], or [[abdominal pain]] and tenderness.<ref>{{Cite journal |last=Sinicrope |first=Frank A. |date=2003 |title=Typhlitis |url=https://www.ncbi.nlm.nih.gov/books/NBK12821/ |journal=Holland-Frei Cancer Medicine. 6th Edition |language=en}}</ref>

[[Typhlitis]] is a [[medical emergency]]. It has a very poor [[prognosis]] and is often fatal unless promptly recognized and aggressively treated.<ref name="Keidan 1989 206–9">{{cite journal | vauthors = Keidan RD, Fanning J, Gatenby RA, Weese JL | title = Recurrent typhlitis. A disease resulting from aggressive chemotherapy | journal = Diseases of the Colon and Rectum | volume = 32 | issue = 3 | pages = 206–9 | date = March 1989 | pmid = 2920627 | doi = 10.1007/BF02554529 | s2cid = 46090832 }}</ref> Successful treatment hinges on early diagnosis provided by a high index of suspicion and the use of CT scanning, nonoperative treatment for uncomplicated cases, and sometimes elective right [[hemicolectomy]] to prevent recurrence.<ref name="Keidan 1989 206–9" />