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===High blood pressure=== A meta-analysis showed that <small>L</small>-arginine reduces blood pressure with pooled estimates of 5.4 mmHg for systolic blood pressure and 2.7 mmHg for diastolic blood pressure.<ref>{{cite journal | vauthors = Dong JY, Qin LQ, Zhang Z, Zhao Y, Wang J, Arigoni F, Zhang W |display-authors=3| title = Effect of oral L-arginine supplementation on blood pressure: a meta-analysis of randomized, double-blind, placebo-controlled trials | journal = American Heart Journal | volume = 162 | issue = 6 | pages = 959β65 | date = December 2011 | pmid = 22137067 | doi = 10.1016/j.ahj.2011.09.012 | department = review }}</ref> Supplementation with {{sm|l}}-arginine reduces [[diastolic blood pressure]] and lengthens pregnancy for women with [[gestational hypertension]], including women with high blood pressure as part of [[pre-eclampsia]]. It did not lower systolic blood pressure or improve [[Birth weight|weight at birth]].<ref>{{cite journal | vauthors = Gui S, Jia J, Niu X, Bai Y, Zou H, Deng J, Zhou R |display-authors=3| title = Arginine supplementation for improving maternal and neonatal outcomes in hypertensive disorder of pregnancy: a systematic review | journal = Journal of the Renin-Angiotensin-Aldosterone System | volume = 15 | issue = 1 | pages = 88β96 | date = March 2014 | pmid = 23435582 | doi = 10.1177/1470320313475910 | department = (review) | doi-access = free }}</ref>
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