Editing Antidepressant (section)

===Other uses===
Antidepressants may be modestly helpful for treating people who have both depression and [[alcohol dependence]], however, the evidence supporting this association is of low quality.<ref>{{cite journal|vauthors=Agabio R, Trogu E, Pani PP|title=Antidepressants for the treatment of people with co-occurring depression and alcohol dependence|journal=The Cochrane Database of Systematic Reviews|volume=2018|issue=4|pages=CD008581|date=April 2018|pmid=29688573|pmc=6494437|doi=10.1002/14651858.CD008581.pub2}}</ref> Bupropion is used to help people [[Smoking cessation|stop smoking]]. Antidepressants are also used to control some symptoms of [[narcolepsy]].<ref>{{cite web|url=https://www.ninds.nih.gov/Disorders/All-Disorders/Narcolepsy-Information-Page|title=Narcolepsy Information Page|date=27 March 2019|website=National Institute of Neurological Disorders and Stroke|access-date=11 April 2020}}</ref> Antidepressants may be used to relieve pain in people with active [[rheumatoid arthritis]]. However, further research is required.<ref>{{cite journal|vauthors=Richards BL, Whittle SL, Buchbinder R|title=Antidepressants for pain management in rheumatoid arthritis|journal=The Cochrane Database of Systematic Reviews|issue=11|pages=CD008920|date=November 2011|pmid=22071859|doi=10.1002/14651858.CD008920.pub2}}</ref> Antidepressants have been shown to be superior to placebo in treating depression in individuals with physical illness, although reporting bias may have exaggerated this finding.<ref>{{cite journal|vauthors=Rayner L, Price A, Evans A, Valsraj K, Higginson IJ, Hotopf M|title=Antidepressants for depression in physically ill people|journal=The Cochrane Database of Systematic Reviews|issue=3|pages=CD007503|date=March 2010|pmid=20238354|doi=10.1002/14651858.CD007503.pub2}}</ref> Antidepressants have been shown to improve some parts of cognitive functioning for depressed users, such as memory, attention, and processing speed.<ref>{{cite journal|vauthors=Prado CE, Watt S, Crowe SF|title=A meta-analysis of the effects of antidepressants on cognitive functioning in depressed and non-depressed samples|journal=Neuropsychology Review|volume=28|issue=1|pages=32–72|date=March 2018|pmid=29446012|doi=10.1007/s11065-018-9369-5}}</ref>

Certain antidepressants acting as serotonin 5-HT<sub>2A</sub> receptor antagonists, such as [[trazodone]] and [[mirtazapine]], have been used as [[trip killer|hallucinogen antidotes or "trip killers"]] to block the effects of [[serotonergic psychedelic]]s like [[psilocybin]] and [[lysergic acid diethylamide]] (LSD).<ref name="HalmanKongSarris2024">{{cite journal|vauthors=Halman A, Kong G, Sarris J, Perkins D|title=Drug-drug interactions involving classic psychedelics: A systematic review|journal=J Psychopharmacol|volume=38|issue=1|pages=3–18|date=January 2024|pmid=37982394|pmc=10851641|doi=10.1177/02698811231211219}}</ref><ref name="YatesMelon2024">{{cite journal|vauthors=Yates G, Melon E|title=Trip-killers: a concerning practice associated with psychedelic drug use|journal=Emerg Med J|volume=41|issue=2|pages=112–113|date=January 2024|pmid=38123961|doi=10.1136/emermed-2023-213377 | url=https://web.archive.org/web/20250511111827oe_/https://s3.amazonaws.com/crawl.prod.proquest.com/fpcache/71f445805bfb61341cbc438c8ae23bd3.pdf?X-Amz-Security-Token=IQoJb3JpZ2luX2VjEBMaCXVzLWVhc3QtMSJIMEYCIQDETX7YpaG5THA%2FNbKR0d92wr6h%2Bgg9preNcKjAsEqo%2BQIhAIlPGGWOeUc23LqhBzRYbxvSXB9aqSe2vVonl4nacAhhKp0CCLz%2F%2F%2F%2F%2F%2F%2F%2F%2F%2FwEQABoMNTE4MzQ2ODQ4MzQxIgy9ji58Qtbi%2BavuKeYq8QEDL1U5KZDQ0bXFyVapeqJgE%2FX6x8DcJfFU8DAXYZPSQEwrIdfPbZWcYsH340deru%2FUHnNaGGpuHFoVzui%2FMbqBz7MANcowj%2FL1%2BQZzQ5hXh5KM3BW8E6NRzrQyuPRmBy7kQUkx8%2BjTN%2BXSMgF%2FCAs6Dn9fScgBGz3ddkwRZXDkjasqMP65RCPKhagK68cyMbf3oX%2BKS8a4Kltc2rk3CnWEhOKrZU4mIxq07DikLAXQbl8YRZJIkeOhN5TgBaLWJqyn1td2VWCMymAaFsqtPWHwXnEfsolRlfDooe6QXfE2YwX5PxBVJU7GPXRgrAqPjwtJMOCHgsEGOpwBYif%2BaDMBdz3IEghuvCvorAS0mkHzdcOz%2Fi7AzuN9nch%2FIm8llhMsN41aAWHuSG25pnhhftauFsg7rbGsrW2nl2kq2upi9zP7y%2Fnqk93jcP0kr0jM8zU12bYoSTsToQJsshH4N%2BTQUMwlzRQfeVv8MXdq%2BgSTTzJrWNwT1yNzye3rSHjvOumbNl6sgBISw7QqRzhB6hZTuf8AcI%2B7&X-Amz-Algorithm=AWS4-HMAC-SHA256&X-Amz-Date=20250511T111826Z&X-Amz-SignedHeaders=host&X-Amz-Credential=ASIAXRL7BHBKRAKCQVVB%2F20250511%2Fus-east-1%2Fs3%2Faws4_request&X-Amz-Expires=3600&X-Amz-Signature=20bb1b90e4c8dbaa4115c954387617ebe2f55269bdd517692f1380193ed3f769}}</ref><ref name="Suran2024">{{cite journal|vauthors=Suran M|title=Study Finds Hundreds of Reddit Posts on "Trip-Killers" for Psychedelic Drugs|journal=JAMA|volume=331|issue=8|pages=632–634|date=February 2024|pmid=38294772|doi=10.1001/jama.2023.28257}}</ref>