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=== Antibiotics === Most people who have an uncomplicated skin abscess should not use antibiotics.<ref name="ACEPfive"/> Antibiotics in addition to standard incision and drainage is recommended in persons with severe abscesses, many sites of infection, rapid disease progression, the presence of [[cellulitis]], symptoms indicating bacterial illness throughout the body, or a health condition causing [[immunosuppression]].<ref name=NEJM2014/> People who are very young or very old may also need antibiotics.<ref name=NEJM2014/> If the abscess does not heal only with incision and drainage, or if the abscess is in a place that is difficult to drain such as the face, hands, or genitals, then antibiotics may be indicated.<ref name=NEJM2014/> In those cases of abscess which do require antibiotic treatment, ''[[Staphylococcus aureus]]'' bacteria is a common cause and an anti-staphylococcus antibiotic such as [[flucloxacillin]] or [[dicloxacillin]] is used. The [[Infectious Diseases Society of America]] advises that the draining of an abscess is not enough to address community-acquired [[Methicillin-resistant Staphylococcus aureus|methicillin-resistant ''Staphylococcus aureus'']] (MRSA), and in those cases, traditional antibiotics may be ineffective.<ref name=NEJM2014/> Alternative antibiotics effective against community-acquired MRSA often include [[clindamycin]], [[doxycycline]], [[minocycline]], and [[trimethoprim-sulfamethoxazole]].<ref name=NEJM2014/> The [[American College of Emergency Physicians]] advises that typical cases of abscess from MRSA get no benefit from having antibiotic treatment in addition to the standard treatment.<ref name="ACEPfive"/> [[Cell culture|Culturing the wound]] is not needed if standard follow-up care can be provided after the incision and drainage.<ref name="ACEPfive"/> Performing a wound culture is unnecessary because it rarely gives information which can be used to guide treatment.<ref name="ACEPfive"/>
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