Editing Turmeric (section)

==Medical research==
{{see also|Curcumin|label 1=Curcumin}}

Turmeric and curcumin have been studied in numerous [[clinical trial]]s for various human diseases and conditions, with no high-quality evidence of any anti-disease effect or health benefit.<ref name=nelson/><ref name=nccih/><ref>{{cite journal|pmid=27533649|pmc=5003001|year=2016|last1=Daily|first1=JW|title=Efficacy of Turmeric Extracts and Curcumin for Alleviating the Symptoms of Joint Arthritis: A Systematic Review and Meta-Analysis of Randomized Clinical Trials|journal=Journal of Medicinal Food|volume=19|issue=8|pages=717–29|last2=Yang|first2=M|last3=Park|first3=S|doi=10.1089/jmf.2016.3705}}</ref><ref>{{cite journal|pmid=27213821|year=2016|last1=Vaughn|first1=A. R.|title=Effects of Turmeric (Curcuma longa) on Skin Health: A Systematic Review of the Clinical Evidence|journal=Phytotherapy Research|volume=30|issue=8|pages=1243–64|last2=Branum|first2=A|last3=Sivamani|first3=RK
|doi=10.1002/ptr.5640|s2cid=46429012}}</ref> There is no scientific evidence that curcumin reduces [[inflammation]], {{as of | 2020| lc=yes}}.<ref name=nelson/><ref name=nccih/><ref>{{cite journal |vauthors=White CM, Pasupuleti V, Roman YM, Li Y, Hernandez AV |display-authors=3|title=Oral turmeric/curcumin effects on inflammatory markers in chronic inflammatory diseases: A systematic review and meta-analysis of randomized controlled trials |journal=Pharmacol Res |volume=146 |pages=104280 |date=August 2019 |pmid=31121255 |doi=10.1016/j.phrs.2019.104280 |s2cid=163166501|type=Meta-analysis}}</ref> There is weak evidence that turmeric extracts may be beneficial for relieving symptoms of knee [[osteoarthritis]],<ref>{{cite journal |vauthors=Wang Z, Singh A, Jones G, Winzenberg T, Ding C, Chopra A, Das S, Danda D, Laslett L, Antony B |display-authors=3|title=Efficacy and Safety of Turmeric Extracts for the Treatment of Knee Osteoarthritis: a Systematic Review and Meta-analysis of Randomised Controlled Trials |journal=Curr Rheumatol Rep |volume=23 |issue=2 |pages=11 |date=January 2021 |pmid=33511486 |doi=10.1007/s11926-020-00975-8 |s2cid=231724282 |url=https://eprints.utas.edu.au/37096/1/Turmeric%20Manuscript.SLK_clean.pdf|archive-url=https://web.archive.org/web/20230526215752/https://eprints.utas.edu.au/37096/1/Turmeric%20Manuscript.SLK_clean.pdf|archive-date=May 26, 2023}}</ref> as well as for reducing pain and muscle damage following physical exercise.<ref>{{Cite journal |last1=Suhett |first1=Lara Gomes |last2=de Miranda Monteiro Santos |first2=Rodrigo |last3=Silveira |first3=Brenda Kelly Souza |last4=Leal |first4=Arieta Carla Gualandi |last5=de Brito |first5=Alice Divina Melo |last6=de Novaes |first6=Juliana Farias |last7=Lucia |first7=Ceres Mattos Della |display-authors=3|date=2021 |title=Effects of curcumin supplementation on sport and physical exercise: a systematic review |url=https://pubmed.ncbi.nlm.nih.gov/32282223/ |journal=Critical Reviews in Food Science and Nutrition |volume=61 |issue=6 |pages=946–958 |doi=10.1080/10408398.2020.1749025 |issn=1549-7852 |pmid=32282223|s2cid=215759520 }}</ref> There is good evidence that turmeric is an allergen.<ref name="pmid26705440">{{cite journal |vauthors=Chaudhari SP, Tam AY, Barr JA |title=Curcumin: A Contact Allergen |journal=J Clin Aesthet Dermatol |volume=8 |issue=11 |pages=43–8 |date=November 2015 |pmid=26705440 |pmc=4689497 |doi= |url=}}</ref>

Although turmeric is of low [[bioavailability]], some supplements boost potency via a variety of preparation techniques. Turmeric supplements are hepatotoxic and have caused a recorded rise in incidence of [[herb-induced liver injury]]. In Italy, the government has banned any claims of turmeric health benefits and mandated warning for turmeric-based supplements.<ref name=hepa>{{cite journal |vauthors=Philips CA, Theruvath AH |title=A comprehensive review on the hepatotoxicity of herbs used in the Indian (Ayush) systems of alternative medicine |journal=Medicine (Baltimore) |volume=103 |issue=16 |pages=e37903 |date=April 2024 |pmid=38640296 |pmc=11029936 |doi=10.1097/MD.0000000000037903 |url=}}</ref>