Editing Rudolf Virchow (section)

===Autopsy===
Virchow was the first to develop a systematic method of autopsy, based on his knowledge of cellular pathology. The modern autopsy still constitutes his techniques.<ref>{{cite web|title=Autopsy: History of autopsy|url=http://www.britannica.com/EBchecked/topic/45129/autopsy|website=Encyclopædia Britannica|access-date=26 November 2014|archive-date=28 April 2015|archive-url=https://web.archive.org/web/20150428233654/http://www.britannica.com/EBchecked/topic/45129/autopsy|url-status=live}}</ref> His first significant autopsy was on a 50-year-old woman in 1845. He found an unusual number of white blood cells, and gave a detailed description in 1847 and named the condition as ''leukämie''.<ref>{{cite journal|title=Rudolf Virchow (1821–1902)|journal=CA: A Cancer Journal for Clinicians|year=1975|volume=25|issue=2|pages=91–92|doi=10.3322/canjclin.25.2.91|pmid=804974|s2cid=1806845|doi-access=free}}</ref> One on his autopsies in 1857 was the first description of [[Vertebral compression fracture|vertebral disc rupture]].<ref name=weller21/><ref>{{cite book|last1=Maurice-Williams|first1=R.S.|title=Spinal Degenerative Disease|year=2013|publisher=Butterworth-Heinemann|isbn=978-1-4831-9340-3|page=2|url=https://books.google.com/books?id=PrzYBAAAQBAJ|access-date=11 September 2017|archive-date=17 April 2022|archive-url=https://web.archive.org/web/20220417013345/https://books.google.com/books?id=PrzYBAAAQBAJ|url-status=live}}</ref> His autopsy on a baby in 1856 was the first description of congenital pulmonary [[lymphangiectasia]] (the name given by K. M. Laurence a century later), a rare and fatal disease of the lung.<ref>{{cite journal|last1=Hwang|first1=Joon Ho|last2=Kim|first2=Joo Heon|last3=Hwang|first3=Jung Ju|last4=Kim|first4=Kyu Soon|last5=Kim|first5=Seung Yeon|title=Pneumonectomy case in a newborn with congenital pulmonary lymphangiectasia|journal=Journal of Korean Medical Science|year=2014|volume=29|issue=4|pages=609–613|doi=10.3346/jkms.2014.29.4.609|pmid=24753713|pmc=3991809}}</ref> From his experience of post-mortem examinations of cadavers, he published his method in a small book in 1876.<ref>{{cite book|last1=Saukko|first1=Pekka J|last2=Pollak|first2=Stefan|chapter=Autopsy|title=Wiley Encyclopedia of Forensic Science|year=2009|volume=John Wiley & Sons, Ltd.|doi=10.1002/9780470061589.fsa036|isbn=978-0-470-01826-2}}</ref> His book was the first to describe the techniques of autopsy specifically to examine abnormalities in organs, and retain important tissues for further examination and demonstration. Unlike any other earlier practitioner, he practiced complete surgery of all body parts with body organs dissected one by one. This has become the standard method.<ref>{{cite book|last1=Finkbeiner|first1=Walter E|last2=Ursell|first2=Philip C|last3=Davis|first3=Richard L|title=Autopsy Pathology: A Manual and Atlas|year=2009|publisher=Elsevier Health Sciences|location=Philadelphia|isbn=978-1-4160-5453-5|page=6|edition=2nd|url=https://books.google.com/books?id=KiGOSz9eGeUC|access-date=27 January 2016|archive-date=17 April 2022|archive-url=https://web.archive.org/web/20220417165549/https://books.google.com/books?id=KiGOSz9eGeUC|url-status=live}}</ref><ref>{{cite journal|last1=Skowronek|first1=R|last2=Chowaniec|first2=C|title=The evolution of autopsy technique—from Virchow to Virtopsy|journal=Archiwum Medycyny Sadowej I Kryminologii|year=2010|volume=60|issue=1|pages=48–54|pmid=21180108}}</ref>

====Ochronosis====

Virchow discovered the clinical syndrome which he called [[ochronosis]], a metabolic disorder in which a patient accumulates [[homogentisic acid]] in connective tissues and which can be identified by discolouration seen under the microscope. He found the unusual symptom in an autopsy of the corpse of a 67-year-old man on 8 May 1884. This was the first time this abnormal disease affecting cartilage and connective tissue was observed and characterised. His description and coining of the name appeared in the October 1866 issue of ''Virchows Archiv''.<ref>{{cite journal|last1=Virchow|first1=RL|title=Rudolph Virchow on ochronosis.1866.|journal=Arthritis and Rheumatism|year=1966|orig-year=1866|volume=9|issue=1|pages=66–71|pmid=4952902|doi=10.1002/art.1780090108}}</ref><ref>{{cite journal|last1=Benedek|first1=Thomas G.|title=Rudolph virchow on ochronosis|journal=Arthritis & Rheumatism|year=1966|volume=9|issue=1|pages=66–71|doi=10.1002/art.1780090108|pmid=4952902}}</ref><ref>{{cite journal|last1=Wilke|first1=Andreas|last2=Steverding|first2=Dietmar|title=Ochronosis as an unusual cause of valvular defect: a case report|journal=Journal of Medical Case Reports|year=2009|volume=3|issue=1|pages=9302|doi=10.1186/1752-1947-3-9302|pmid=20062791|pmc=2803825 |doi-access=free }}</ref>