Editing Psilocybin (section)

===Onset and duration===
The [[onset of action]] of psilocybin taken [[oral administration|orally]] is 0.5 to 0.8{{nbsp}}hours (30–50{{nbsp}}minutes) on average, with a range of 0.1 to 1.5{{nbsp}}hours (5–90{{nbsp}}minutes).<ref name="HolzeSinghLiechti2024" /><ref name="MacCallumLoPistawka2022" /> Peak [[psychoactive drug|psychoactive]] effects occur at about 1.0 to 2.2{{nbsp}}hours (60–130{{nbsp}}minutes).<ref name="MacCallumLoPistawka2022" /><ref name="HolzeSinghLiechti2024" /> The [[time to offset]] of psilocybin orally is about 6 to 7{{nbsp}}hours on average.<ref name="HolzeBeckerKolaczynska2023" /> The [[duration of action]] of psilocybin is about 4 to 6{{nbsp}}hours (range 3–12{{nbsp}}hours) orally.<ref name="MacCallumLoPistawka2022" /><ref name="HolzeSinghLiechti2024" /><ref name="YerubandiThomasBhuiya2024">{{cite journal | vauthors = Yerubandi A, Thomas JE, Bhuiya NM, Harrington C, Villa Zapata L, Caballero J | title = Acute Adverse Effects of Therapeutic Doses of Psilocybin: A Systematic Review and Meta-Analysis | journal = JAMA Network Open | volume = 7 | issue = 4 | pages = e245960 | date = April 2024 | pmid = 38598236 | pmc = 11007582 | doi = 10.1001/jamanetworkopen.2024.5960 | quote = When selecting adverse event profile rates, the shortest time period available was selected and analyzed (eg, day 1 instead of day 30) since the half-life of psilocin is 3 ± 1.1 hours when taken orally and the duration of action can range between 3 to 12 hours.12,13 }}</ref> A small dose of 1{{nbsp}}mg by [[intravenous injection]] had a duration of 15 to 30{{nbsp}}minutes.<ref name="Passie2002" /><ref name="HaslerBourquinBrenneisen1997" />