Editing Protein (section)

=== Protein domains ===

{{Main|Protein domain}}

Many proteins are composed of several [[protein domain]]s, i.e. segments of a protein that fold into distinct structural units.<ref name=Biochemistry2010>{{Cite book |last1=Garrett |first1=R. |title=Biochemistry |last2=Grisham |first2=Charles M. |date=2010 |publisher=Brooks/Cole, Cengage Learning |isbn=978-0-495-10935-8 |edition=4th |location=Belmont, CA}}</ref>{{rp|134}} Domains usually have specific functions, such as [[Enzyme|enzymatic]] activities (e.g. [[kinase]]) or they serve as binding modules.<ref name=Biochemistry2010 />{{rp|155–156}}

[[File:Domain organisation of EVH proteins.png|frame|'''Protein domains vs. motifs'''. Protein domains (such as the [[WH1 domain|EVH1 domain]]) are functional units within proteins that fold into defined 3D structures. Motifs are usually short sequences with specific functions but without a stable 3D structure. Many motifs are binding sites for other proteins (such as the red and green bars shown here in the context of a [[Ena/Vasp homology proteins|VASP]] protein).<ref>{{Cite journal |last1=Drees |first1=Frauke |last2=Gertler |first2=Frank B |date=2008-02-01 |title=Ena/VASP: proteins at the tip of the nervous system |journal=Current Opinion in Neurobiology |series=Development |volume=18 |issue=1 |pages=53–59 |doi=10.1016/j.conb.2008.05.007  |pmc=2515615 |pmid=18508258}}</ref>|center]]