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==Terminology== In the United States and Canada, the term ''motor neuron disease'' usually refers to the group of disorders while amyotrophic lateral sclerosis is frequently called ''Lou Gehrig's disease''.<ref name=NINDS2014/><ref name=":14">{{Cite book |title=Clinical and molecular aspects of motor neuron disease | vauthors = Cooper-Knock J, Jenkins T, Shaw PJ |isbn=978-1-61504-429-0|location=San Rafael, California |oclc=860981760|date = 2013-09-01}}</ref><ref name=":3">{{cite journal | vauthors = Shaw PJ | title = Molecular and cellular pathways of neurodegeneration in motor neurone disease | journal = Journal of Neurology, Neurosurgery, and Psychiatry | volume = 76 | issue = 8 | pages = 1046β1057 | date = August 2005 | pmid = 16024877 | pmc = 1739758 | doi = 10.1136/jnnp.2004.048652 | quote = Many doctors use the terms motor neuron disease and ALS interchangeably. }}</ref> In the United Kingdom and Australia, the term ''motor neuron(e) disease'' is used for amyotrophic lateral sclerosis,<ref name="NHS"/><ref name="healthdirectAU"/> although is not uncommon to refer to the entire group.<ref name=":15">{{cite web |url=https://www.mndassociation.org/wp-content/uploads/2015/02/an-introduction-to-mnd-booklet.pdf |archive-url=https://ghostarchive.org/archive/20221009/https://www.mndassociation.org/wp-content/uploads/2015/02/an-introduction-to-mnd-booklet.pdf |archive-date=2022-10-09 |url-status=live|title=An introduction to motor neurone disease (MND) |website=motor neurone disease association|date= 2015}}</ref><ref>{{Cite book |title=Neurodegeneration| vauthors = Schapira AH, Wszolek ZK, Dawson TM, Wood NW |isbn=978-1-118-66191-8 |location=Chichester, West Sussex |oclc=958876527 | date = 2017-02-13 }}</ref> While MND refers to a specific subset of similar diseases, there are numerous other diseases of [[motor neuron]]s that are referred to collectively as "motor neuron disorders", for instance the diseases belonging to the [[spinal muscular atrophies]] group.<ref name=El2008>{{cite book | vauthors = Ince PG, Clark B, Holton J, Revesz T, Wharton SB | chapter = Chapter 13: Diseases of movement and system degenerations | veditors = Greenfield JG, Love S, Louis DN, Ellison DW |title=Greenfield's neuropathology|date=2008|publisher=Hodder Arnold|location=London|isbn=978-0-340-90681-1 | volume = 1 |page=947|edition=8th|chapter-url=https://books.google.com/books?id=nrEWkAc7W7IC&pg=PA947}}</ref> However, they are not classified as "motor neuron diseases" by the 11th edition of the [[International Statistical Classification of Diseases and Related Health Problems]] (ICD-11),<ref>{{Cite web|url=https://icd.who.int/browse11/l-m/en#/http%3a%2f%2fid.who.int%2ficd%2fentity%2f661720689|title=8B60 Motor neuron disease|website=ICD-11 for Mortality and Morbidity Statistics|publisher=World Health Organisation}}</ref> which is the definition followed in this article.
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