Editing Lymph node (section)

===Cancer===
[[File:Crc met to node1.jpg|thumb|200px|right|[[Micrograph]] of a [[mesenteric lymph node]] with [[adenocarcinoma]]]]
Lymph nodes can be affected by both primary [[cancer]]s of lymph tissue, and secondary cancers affecting other parts of the body. Primary cancers of lymph tissue are called lymphomas and include [[Hodgkin lymphoma]] and [[non-Hodgkin lymphoma]].{{sfn|Davidson's|2018|p=961}} Cancer of lymph nodes can cause a wide range of symptoms from painless long-term slowly growing swelling to sudden, rapid enlargement over days or weeks, with symptoms depending on the [[tumour grade|grade]] of the tumour.{{sfn|Davidson's|2018|p=961}} Most lymphomas are tumours of B-cells.{{sfn|Davidson's|2018|p=961}} Lymphoma is managed by [[Hematology|haematologists]] and [[Oncology|oncologists]].

Local cancer in many parts of the body can cause lymph nodes to enlarge because of tumorous cells that have [[metastasis]]ed into the node.{{sfn|Davidson's|2018|p=1324}} Lymph node involvement is often a key part in the diagnosis and treatment of cancer, acting as "[[Sentinel lymph node|sentinels]]" of local disease, incorporated into [[TNM staging]] and other [[cancer staging]] systems. As part of the investigations or [[Medical diagnosis#Other diagnostic procedure methods|workup]] for cancer, lymph nodes may be imaged or even surgically removed. If removed, the lymph node will be stained and examined under a microscope by a [[Pathology|pathologist]] to determine if there is evidence of cells that appear cancerous (i.e. have metastasized into the node). The staging of the cancer, and therefore the treatment approach and prognosis, is predicated on the presence of node metastases.