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Essential tremor
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====Beta-adrenergic Blockers==== [[File:Propranolol.svg|thumb|Chemical structure of Propranolol, one of the most effective medication for treating ET]] When symptoms are sufficiently troublesome to warrant treatment, the first choice medication is [[propranolol]], a non-selective beta-blocker, which has been shown effective in reducing tremor by 70% in 50% of patients in clinical studies.<ref name=":7">{{cite journal | vauthors = Sharma S, Pandey S | title = Treatment of essential tremor: current status | journal = Postgraduate Medical Journal | volume = 96 | issue = 1132 | pages = 84β93 | date = February 2020 | pmid = 31575730 | doi = 10.1136/postgradmedj-2019-136647 }}</ref> Based on the guidelines from the American Academy of Neurology and the Italian Movement Disorders Association, propranolol is most effective in limb tremors, also there is little to no effect on head tremors. The recommended doses of propranolol range from 60 to 360 mg daily, and it is based on the patient's specific factors.<ref name=":7" /> The commonly reported side effects of propranolol are bradycardia, bronchospasm, fatigue, and hypotension.<ref name=":8">{{cite journal | vauthors = Patel MD, Patel M, Jani R, Patel KG, Patel P, Gandhi SK | title = Essential Tremors: A Literature Review of Current Therapeutics | journal = Cureus | volume = 16 | issue = 5 | pages = e59451 | date = May 2024 | pmid = 38826876 | pmc = 11141324 | doi = 10.7759/cureus.59451 | doi-access = free }}</ref> In patients that have contraindicated comorbidities to propranolol, other beta-blockers such as [[Atenolol]], [[pindolol]], [[Sotalol]], and [[nadolol]] have shown some potential efficacy, but they are not very well studied and have limited evidence in their efficacy on the treatment of ET.<ref name=":0" />
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