Editing Ehlers–Danlos syndrome (section)

===Myopathic===
[[Bethlem myopathy|Bethlem myopathy 2]], formally known as Myopathic EDS (mEDS), is characterized by three major criteria: congenital muscle [[hypotonia]] and/or [[muscle atrophy]] that improves with age, proximal joint contractures of the knee, hip, and elbow, and hypermobility of distal joints (ankles, wrists, feet, and hands).<ref name=GARD2017/> Four minor criteria may also contribute to a diagnosis of mEDS. This disorder can be inherited through either an autosomal dominant or an autosomal recessive pattern.<ref name="EDS_2019" /> Molecular testing must be completed to verify that mutations in the ''[[COL12A1]]'' gene are present; if not, other collagen-type myopathies should be considered.<ref name="EDS_2019" />