Editing Dengue fever (section)

== Severe disease ==
The [[World Health Organization]]'s [[International Classification of Diseases]] divides dengue fever into two classes: uncomplicated and severe.<ref name="White10" /> '''Severe dengue''' is defined as that associated with severe bleeding, severe organ dysfunction, or severe plasma leakage.<ref>{{Cite web |date=1 January 2022 |title=International Classification of Diseases (ICD-11) |url=https://www.who.int/standards/classifications/classification-of-diseases |access-date=2024-02-28 |website=World Health Organization |language=en |archive-date=20 September 2023 |archive-url=https://web.archive.org/web/20230920045132/https://www.who.int/standards/classifications/classification-of-diseases |url-status=live }}</ref>

Severe dengue can develop suddenly, sometimes after a few days as the fever subsides.<ref name="Mayo-Clinic-Symptoms-2024" /> Leakage of plasma from the capillaries results in extreme [[Hypotension|low blood pressure]] and [[hypovolemic shock]];  Patients with severe plasma leakage may have fluid accumulation in the [[Pleural effusion|lungs]] or [[Ascites|abdomen]], [[Hypoproteinemia|insufficient protein in the blood]], or [[Hematocrit|thickening of the blood]]. Severe dengue is a medical emergency which can cause damage to organs, leading to multiple organ failure and death.<ref>{{Cite web |last=CDC |date=2023-04-13 |title=Dengue Clinical Presentation {{!}} CDC |url=https://www.cdc.gov/dengue/healthcare-providers/clinical-presentation.html |access-date=2024-02-29 |website=Centers for Disease Control and Prevention |language=en-us |archive-date=29 February 2024 |archive-url=https://web.archive.org/web/20240229211732/https://www.cdc.gov/dengue/healthcare-providers/clinical-presentation.html |url-status=live }}</ref>