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==History== [[File:Plantar wart papilloma.jpg|thumb|right|A ~7 mm plantar wart surgically removed from the sole of a person's foot after other treatments failed.]] Surviving ancient medical texts show that warts were a documented disease since at least the time of [[Hippocrates]], who lived {{circa|460}} β {{circa|370 BC}}. In the book ''De Medecia'' by the Roman physician [[Aulus Cornelius Celsus]], who lived {{circa|25 BC}} β {{circa|50 AD}}, different types of warts were described. Celsus described ''Myrmecia'', today recognized as [[plantar wart]], and categorized [[acrochordon]] (a skin tag) as a wart. In the 13th century, warts were described in books published by the surgeons [[William of Saliceto]] and [[Lanfranc of Milan]]. The word ''[[verruca]]'' to describe a wart was introduced by the physician [[Daniel Sennert]], who described warts in his 1636 book ''Hypomnemata physicae''.<ref name="link.springer.com">{{cite journal|first1=Marianna |last1=Karamanou |first2=Emmanovil | last2= Agapitos| first3=Antonis |last3=Kousoulis| first4=George| last4=Androutsos |title=From the humble wart to HPV: a fascinating story throughout centuries|date=17 August 2010|journal=Oncology Reviews|volume=4|issue=3 |pages=133β135|doi= 10.1007/s12156-010-0060-1|s2cid=72238300 |doi-access=free}}</ref> The cause of warts was initially disputed in the medical profession. In the early 18th century the physician [[Daniel Turner (physician)|Daniel Turner]], who published the first book on [[dermatology]], suggested that warts were caused by damaged [[nerve]]s close to the skin. In the mid-18th century, the surgeon [[John Hunter (surgeon)|John Hunter]] popularized the belief that warts were caused by a bacterial [[syphilis]] infection. The surgeon [[Benjamin Bell]] documented that warts were caused by a disease entirely unrelated to syphilis, and established a [[Correlation and dependence|causal link]] between warts and cancer. In the 19th century, the [[chief physician]] of Verona Hospital established a link between warts and [[cervical cancer]]. But in 1874 it was noted by the dermatologist [[Ferdinand Ritter von Hebra]] that while various theories were advanced by the medical profession, the "influences causing warts are still very obscure".<ref name="link.springer.com"/> In 1907 the physician Giuseppe Ciuffo was the first to demonstrate that warts were caused by a virus infection. In 1976 the virologist [[Harald zur Hausen]] was the first to discover that warts were caused by the [[human papillomavirus]] (HPV). His continuous research established the evidence necessary to develop a [[HPV vaccine]], which first became available in 2006.<ref name="link.springer.com"/>
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