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==Mechanical stress== Wounds under 2 millimeters generally do not scar,<ref name=pmid17586870/><ref name=smallWound/> but larger wounds generally do scar.<ref name=pmid17586870/><ref name=smallWound/> In 2011, it was found that mechanical stress can stimulate scarring<ref name=scarStress2011/> and that stress shielding can reduce scarring in wounds.<ref name=scarStress2011/><ref name=scarStressRev/> In 2021, it was found that using chemicals to manipulate fibroblasts to not sense mechanical stress brought scar-free healing.<ref name=chemMech2021/> The scar-free healing also occurred when mechanical stress was placed onto a wound.<ref name=chemMech2021>{{cite web | url =https://www.statnews.com/2021/04/22/scientists-unlock-key-to-scar-free-skin-healing/ | title = In mouse experiments, scientists unlock the key to scar-free skin healing| last =Molteni | first =Megan | date =22 April 2021 | website = statnews.com| publisher = | access-date = 1 May 2021 | quote = }}</ref>
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