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==== Enhancer RNAs ==== {{See also|Enhancer RNA}} The third major group of regulatory RNAs is called [[enhancer RNA]]s.<ref name="Rinn-2012" /> It is not clear at present whether they are a unique category of RNAs of various lengths or constitute a distinct subset of lncRNAs. In any case, they are transcribed from [[enhancers]], which are known regulatory sites in the DNA near genes they regulate.<ref name="Rinn-2012" /><ref>{{cite journal | vauthors = Taft RJ, Kaplan CD, Simons C, Mattick JS | year = 2009 | title = Evolution, biogenesis and function of promoter- associated RNAs | journal = Cell Cycle | volume = 8 | issue = 15| pages = 2332β38 | doi = 10.4161/cc.8.15.9154 | pmid = 19597344 | doi-access = free }}</ref> They up-regulate the transcription of the gene(s) under control of the enhancer from which they are transcribed.<ref name="Rinn-2012" /><ref>{{cite journal | vauthors = Orom UA, Derrien T, Beringer M, Gumireddy K, Gardini A | display-authors = etal | year = 2010 | title = 'Long noncoding RNAs with enhancer-like function in human cells | journal = Cell | volume = 143 | issue = 1| pages = 46β58 | pmid = 20887892 | doi = 10.1016/j.cell.2010.09.001 | pmc = 4108080 }}</ref>
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