Editing Paroxetine (section)

==Overdose==
Acute overdosage is often manifested by [[emesis]], [[lethargy]], [[ataxia]], [[tachycardia]], and [[seizures]]. Plasma, serum, or blood concentrations of paroxetine may be measured to monitor therapeutic administration, confirm a diagnosis of poisoning in hospitalized patients or to aid in the medicolegal investigation of fatalities. Plasma paroxetine concentrations are generally in a range of 40–400&nbsp;μg/L in persons receiving daily therapeutic doses and 200–2,000&nbsp;μg/L in poisoned patients. Postmortem blood levels have ranged from 1–4&nbsp;mg/L in acute lethal overdose situations.<ref>{{cite journal | vauthors = Goeringer KE, Raymon L, Christian GD, Logan BK | title = Postmortem forensic toxicology of selective serotonin reuptake inhibitors: a review of pharmacology and report of 168 cases | journal = Journal of Forensic Sciences | volume = 45 | issue = 3 | pages = 633–648 | date = May 2000 | pmid = 10855970 | doi = 10.1520/JFS14740J }}</ref><ref>R. Baselt,''Disposition of Toxic Drugs and Chemicals in Man'', 8th edition, Biomedical Publications, Foster City, CA, 2008, pp. 1190–1193.</ref> Along with the other SSRIs, [[sertraline]] and [[fluoxetine]], paroxetine is considered a low-risk drug in cases of overdose.<ref>{{cite journal | vauthors = White N, Litovitz T, Clancy C | title = Suicidal antidepressant overdoses: a comparative analysis by antidepressant type | journal = Journal of Medical Toxicology | volume = 4 | issue = 4 | pages = 238–250 | date = December 2008 | pmid = 19031375 | pmc = 3550116 | doi = 10.1007/BF03161207 }}</ref>