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==In medicine== A [[paradoxical reaction]] to a [[drug]] is the opposite of what one would expect, such as becoming agitated by a [[sedative]] or sedated by a [[stimulant]]. Some are common and are used regularly in medicine, such as the use of stimulants such as [[Adderall]] and [[Ritalin]] in the treatment of [[attention deficit hyperactivity disorder]] (also known as ADHD), while others are rare and can be dangerous as they are not expected, such as severe agitation from a [[benzodiazepine]].<ref>{{cite journal |vauthors=Wilson MP, Pepper D, Currier GW, Holloman GH, Feifel D |title=The Psychopharmacology of Agitation: Consensus Statement of the American Association for Emergency Psychiatry Project BETA Psychopharmacology Workgroup |journal=Western Journal of Emergency Medicine |volume=13 |issue=1 |pages=26β34 |date=February 2012 |doi=10.5811/westjem.2011.9.6866 |doi-access=free |pmc=3298219 |pmid=22461918}}</ref> The actions of [[antibody|antibodies]] on [[antigen]]s can rarely take paradoxical turns in certain ways. One example is [[antibody-dependent enhancement]] (immune enhancement) of a disease's virulence; another is the [[hook effect]] (prozone effect), of which there are several types. However, neither of these problems is common, and overall, antibodies are crucial to health, as most of the time they do their protective job quite well.<!--Acknowledging here for the reader to comprehend these facts within the proper framework of perspective; see the comment nearby below for another example of the same kind of helping the reader with [[critical thinking]].--> In the [[smoker's paradox]], cigarette smoking, despite its [[health effects of tobacco|proven harms]], has a surprising inverse correlation with the epidemiological incidence of certain diseases.
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