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==Treatment== There is no known antidote for pennyroyal toxicity.<ref name="NIH1"/> Case studies involving pennyroyal poisonings have reported the use of [[gastric lavage]]s and administration of [[emetic]]s or [[vomiting]] inducing agents, or absorbents like [[activated charcoal]].<ref name="Ilene">{{cite journal|last1=Ilene|first1=Anderson B.|last2=Walter|first2=Mullen H.|last3=James|first3=Meeker E.|last4=Siamak|first4=Khojasteh-Bakht|last5=Shimako|first5=Oishi|last6=Sidney|first6=Nelson D.|last7=Paul|first7=Blanc D.|s2cid=24375611|title=Pennyroyal Toxicity: Measurement of Toxic Metabolite Levels in Two Cases and Review of the Literature|journal=Annals of Internal Medicine|date=15 April 1996|volume=124|issue=8|pages=726β734|doi=10.7326/0003-4819-124-8-199604150-00004|pmid=8633832}}</ref> As [[glutathione]] depletion has been shown to regulate liver toxification, administration of [[N-acetylcysteine]] in similar doses as given for [[acetaminophen]] toxicity have been given to patients.<ref name="NIH">{{cite web|title=Drug Record Pennyroyal Oil (Mentha Pulegium)|url=https://livertox.nih.gov/Pennyroyal.htm|website=LiverTox|publisher=United States National Library of Medicine|access-date=2017-05-07}}</ref> A study testing pulegone toxicity found inhibitors of cytochrome P450, such as [[cobaltous chloride]] or [[piperonyl butoxide]], blocked toxicity.<ref name="Gordon"/> Such testing has not been expanded to humans, however, as the pennyroyal mechanism of toxicity is still not entirely understood.
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