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===Disorders of glycogen metabolism=== The most common disease in which glycogen [[metabolism]] becomes abnormal is [[diabetes]], in which, because of abnormal amounts of insulin, liver glycogen can be abnormally accumulated or depleted. Restoration of normal glucose metabolism usually normalizes glycogen metabolism, as well. In [[hypoglycemia]] caused by excessive insulin, liver glycogen levels are high, but the high insulin levels prevent the [[glycogenolysis]] necessary to maintain normal blood sugar levels. [[Glucagon]] is a common treatment for this type of hypoglycemia. Various [[inborn errors of carbohydrate metabolism]] are caused by deficiencies of enzymes or transport proteins necessary for glycogen synthesis or breakdown. These are collectively referred to as [[glycogen storage disease]]s.
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