Editing Glucose tolerance test (section)

==Limitations of OGTT==
The OGTT does not distinguish between insulin resistance in peripheral tissues and reduced capacity of the pancreas [[Beta cell|beta-cells]] to produce insulin. The OGTT is less accurate than the [[Glucose clamp technique|hyperinsulinemic-euglycemic clamp technique]] (the "gold standard" for measuring insulin resistance), or the [[insulin tolerance test]], but is technically less difficult. Neither of the two technically demanding tests can be easily applied in a clinical setting or used in epidemiological studies. HOMA-IR ([[homeostatic model assessment]]) is a convenient way of measuring insulin resistance in normal subjects, which can be used in epidemiological studies, but can give erroneous results for diabetic patients.<ref name="pmid17957034">{{cite journal|vauthors=Muniyappa R, Lee S, Chen H, Quon MJ|title=Current approaches for assessing insulin sensitivity and resistance in vivo: advantages, limitations, and appropriate usage|journal=[[American Physiological Society#Publications|American Journal of Physiology. Endocrinology and Metabolism]]|volume=294|issue=1|pages=E15–E26|year=2008|doi=10.1152/ajpendo.00645.2007|url=http://ajpendo.physiology.org/content/294/1/E15.long|pmid=17957034|s2cid=848540|url-access=subscription|access-date=2017-02-13|archive-date=2017-08-17|archive-url=https://web.archive.org/web/20170817172932/http://ajpendo.physiology.org/content/294/1/E15.long|url-status=dead}}</ref><ref name="pmid21435930">{{cite journal|vauthors=Antuna-Puente B, Disse E, Rabasa-Lhoret R, Laville M, Capeau J, Bastard JP|title=How can we measure insulin sensitivity/resistance?|journal= Diabetes & Metabolism|volume=37|issue=5|pages=179–88|year=2011|doi=10.1016/j.diabet.2011.01.002|url=http://www.em-consulte.com/article/296652/alertePM|pmid=21435930}}</ref>