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=== Fertility === {{Main|Fertility}} A meta-analysis provided preliminary evidence that men treated with supplements containing [[selenium in biology|selenium]], [[zinc]], [[omega-3 fatty acid]]s, [[coenzyme Q10|coenzyme Q<sub>10</sub>]] or [[carnitine]]s reported improvements in total sperm count, concentration, motility, and morphology.<ref>{{cite journal | vauthors = Salas-Huetos A, Rosique-Esteban N, Becerra-Tomás N, Vizmanos B, Bulló M, Salas-Salvadó J | title = The Effect of Nutrients and Dietary Supplements on Sperm Quality Parameters: A Systematic Review and Meta-Analysis of Randomized Clinical Trials | journal = Advances in Nutrition | volume = 9 | issue = 6 | pages = 833–48 | date = November 2018 | pmid = 30462179 | doi = 10.1093/advances/nmy057 | pmc = 6247182 }}</ref> A review concluded that omega-3 taken through supplements and diet might improve semen quality in infertile men.<ref>{{cite journal | vauthors = Falsig AL, Gleerup CS, Knudsen UB | title = The influence of omega-3 fatty acids on semen quality markers: a systematic PRISMA review | journal = Andrology | volume = 7 | issue = 6 | pages = 794–803 | date = November 2019 | pmid = 31116515 | doi = 10.1111/andr.12649 | doi-access = free }}</ref> A 2021 review also supported selenium, zinc, omega-3 fatty acids, coenzyme Q<sub>10</sub> or carnitines, but warned that "excessive use of antioxidants may be detrimental to the spermatic function and many of the over-the-counter supplements are not scientifically proven to improve fertility."<ref>{{cite journal | vauthors = Torres-Arce E, Vizmanos B, Babio N, Márquez-Sandoval F, Salas-Huetos A | title = Dietary Antioxidants in the Treatment of Male Infertility: Counteracting Oxidative Stress | journal = Biology | volume = 10 | issue = 3 | page = 241 | date = March 2021 | pmid = 33804600 | pmc = 8003818 | doi = 10.3390/biology10030241 | doi-access = free }}</ref> There is low quality and insufficient evidence for the use of oral antioxidant supplements as a viable treatment for [[subfertile]] woman.<ref>{{cite journal | vauthors = Showell MG, Mackenzie-Proctor R, Jordan V, Hart RJ | title = Antioxidants for female subfertility | journal = The Cochrane Database of Systematic Reviews | volume = 8 | page = CD007807 | date = August 2020 | issue = 11 | pmid = 32851663 | doi = 10.1002/14651858.CD007807.pub4 | collaboration = Cochrane Gynaecology and Fertility Group | pmc = 8094745 }}</ref> A review provided evidence that taking [[Dehydroepiandrosterone (dietary supplement)|dehydroepiandrosterone]] before starting an ''in vitro'' fertilization series may increase pregnancy rates and decrease miscarriage likelihood.<ref>{{cite journal | vauthors = Schwarze JE, Canales J, Crosby J, Ortega-Hrepich C, Villa S, Pommer R | title = DHEA use to improve likelihood of IVF/ICSI success in patients with diminished ovarian reserve: A systematic review and meta-analysis | journal = JBRA Assisted Reproduction | volume = 22 | issue = 4 | pages = 369–74 | date = November 2018 | pmid = 30125071 | pmc = 6210617 | doi = 10.5935/1518-0557.20180046 }}</ref>
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