Editing Ciprofloxacin (section)

===Nervous system===
Because Ciprofloxacin is lipophilic, it has the ability to cross the [[blood–brain barrier]].<ref name="babar2013">{{cite journal |vauthors = Babar SM |title = SIADH associated with ciprofloxacin |journal = The Annals of Pharmacotherapy |volume = 47 |issue = 10 |pages = 1359–63 |date = October 2013 |pmid = 24259701 |doi = 10.1177/1060028013502457 |s2cid = 36759747 }}</ref> The 2013 FDA label warns of nervous system effects. Ciprofloxacin, like other fluoroquinolones, is known to trigger seizures or lower the seizure threshold, and may cause other central nervous system adverse effects. Headache, dizziness, and insomnia have been reported as occurring fairly commonly in postapproval review articles, along with a much lower incidence of serious CNS adverse effects such as tremors, psychosis, anxiety, hallucinations, paranoia, and suicide attempts, especially at higher doses.<ref name=He2013/> Like other fluoroquinolones, it is also known to cause peripheral neuropathy that may be irreversible, such as weakness, burning pain, tingling or numbness.<ref>{{cite web |url=https://www.fda.gov/Drugs/DrugSafety/ucm365050.htm |title=FDA Drug Safety Communication: FDA requires label changes to warn of risk for possibly permanent nerve damage from antibacterial fluoroquinolone drugs taken by mouth or by injection |publisher=U.S. [[Food and Drug Administration]] (FDA) |url-status=dead |archive-url=https://web.archive.org/web/20160528231716/https://www.fda.gov/Drugs/DrugSafety/ucm365050.htm |archive-date=28 May 2016}}</ref>

Fluoroquinolones have already been reported for movement disorders.<ref name=":0" /> In this context, ciprofloxacin is especially associated with [[myoclonus]], which derives the term "ciproclonus."<ref name=":1" />