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=== Therapeutics === Major diseases where altering capillary formation could be helpful include conditions where there is excessive or abnormal capillary formation such as cancer and disorders harming eyesight; and medical conditions in which there is reduced capillary formation either for familial or genetic reasons, or as an acquired problem. * In patients with the retinal disorder, neovascular age-related [[macular degeneration]], local [[anti-VEGF therapy]] to limit the bio-activity of [[vascular endothelial growth factor]] has been shown to protect vision by limiting progression.<ref>{{cite journal |pages=3033β41 |doi=10.1172/JCI42437 |title=Therapeutic targets in age-related macular disease |year=2010 |last1=Bird |first1=Alan C. |journal=Journal of Clinical Investigation |volume=120 |issue=9 |pmid=20811159 |pmc=2929720}}</ref> In a wide range of cancers, treatment approaches have been studied, or are in development, aimed at decreasing tumour growth by reducing angiogenesis.<ref>{{cite journal |pages=3962β73 |doi=10.2741/3504 |title=Tumor angiogenesis and molecular targets for therapy |year=2009 |last1=Cao |first1=Yihai |journal=Frontiers in Bioscience |issue=14 |pmid=19273326 |volume=14|doi-access=free }}</ref>
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