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Autosomal dominant polycystic kidney disease
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===Neurolysis=== A novel treatment of specifically the chronic pain experienced by many with ADPKD is [[Celiac plexus neurolysis]].<ref name="pmid28159317">{{cite journal | vauthors = Casteleijn NF, van Gastel MD, Blankestijn PJ, Drenth JP, de Jager RL, Leliveld AM, Stellema R, Wolff AP, Groen GJ, Gansevoort RT | display-authors = 6 | title = Novel treatment protocol for ameliorating refractory, chronic pain in patients with autosomal dominant polycystic kidney disease | journal = Kidney International | volume = 91 | issue = 4 | pages = 972β981 | date = April 2017 | pmid = 28159317 | doi = 10.1016/j.kint.2016.12.007 | doi-access = free }}</ref><ref>{{cite journal | vauthors = Nitschke AM, Ray CE | title = Percutaneous neurolytic celiac plexus block | journal = Seminars in Interventional Radiology | volume = 30 | issue = 3 | pages = 318β321 | date = September 2013 | pmid = 24436554 | pmc = 3773031 | doi = 10.1055/s-0033-1353485 }}</ref> This involves the chemical ablation of the [[celiac plexus]], to cause a temporary degeneration of targeted nerve fibers. When the nerve fibers degenerate, it causes an interruption in the transmission of nerve signals. This treatment, when successful, provides significant pain relief for a period ranging from a few days to over a year. The procedure may be repeated when the affected nerves have healed and the pain returns.<ref>{{cite journal |title=Response to repeat echoendoscopic celiac plexus neurolysis in pancreatic cancer patients: A machine learning approach |url=https://pubmed.ncbi.nlm.nih.gov/31375433/ |journal=Pancreatology |year=2019 |pmid=31375433 |access-date=5 January 2023|last1=Facciorusso |first1=A. |last2=Del Prete |first2=V. |last3=Antonino |first3=M. |last4=Buccino |first4=V. R. |last5=Muscatiello |first5=N. |volume=19 |issue=6 |pages=866β872 |doi=10.1016/j.pan.2019.07.038 |s2cid=199389236 }}</ref>
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