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===Growth hormone=== Intravenously administered arginine is used in growth hormone stimulation tests<ref>{{MedlinePlusEncyclopedia|003377|Growth hormone stimulation test}}</ref> because it stimulates the secretion of [[growth hormone]].<ref>{{cite journal | vauthors = Alba-Roth J, MΓΌller OA, Schopohl J, von Werder K | s2cid = 7488757 | title = Arginine stimulates growth hormone secretion by suppressing endogenous somatostatin secretion | journal = The Journal of Clinical Endocrinology and Metabolism | volume = 67 | issue = 6 | pages = 1186β9 | date = December 1988 | pmid = 2903866 | doi = 10.1210/jcem-67-6-1186 }}</ref> A review of clinical trials concluded that oral arginine increases growth hormone, but decreases growth hormone secretion, which is normally associated with exercising.<ref>{{cite journal | vauthors = Kanaley JA | title = Growth hormone, arginine and exercise | journal = Current Opinion in Clinical Nutrition and Metabolic Care | volume = 11 | issue = 1 | pages = 50β4 | date = January 2008 | pmid = 18090659 | doi = 10.1097/MCO.0b013e3282f2b0ad | s2cid = 22842434 }}</ref> However, a more recent trial reported that although oral arginine increased plasma levels of <small>L</small>-arginine it did not cause an increase in growth hormone.<ref>{{cite journal | vauthors = Forbes SC, Bell GJ | title = The acute effects of a low and high dose of oral L-arginine supplementation in young active males at rest | journal = Applied Physiology, Nutrition, and Metabolism| volume = 36 | issue = 3 | pages = 405β11 | date = June 2011 | pmid = 21574873 | doi = 10.1139/h11-035 }}</ref>
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