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===Alternative theories=== Levels of [[sulfate-reducing bacteria]] tend to be higher in persons with ulcerative colitis, which could indicate higher levels of [[hydrogen sulfide]] in the intestine. An alternative theory suggests that the symptoms of the disease may be caused by toxic effects of the hydrogen sulfide on the cells lining the intestine.<ref name=Roediger>{{cite journal | vauthors = Roediger WE, Moore J, Babidge W | title = Colonic sulfide in pathogenesis and treatment of ulcerative colitis | journal = Digestive Diseases and Sciences | volume = 42 | issue = 8 | pages = 1571–1579 | date = August 1997 | pmid = 9286219 | doi = 10.1023/A:1018851723920 | s2cid = 25496705 }}</ref> Infection by ''[[Mycobacterium avium]]'', subspecies ''[[paratuberculosis]]'', has been proposed as the ultimate cause of both ulcerative colitis and Crohn's disease.<ref>{{cite journal | vauthors = Pierce ES | title = Could ''Mycobacterium avium'' subspecies ''paratuberculosis'' cause Crohn's disease, ulcerative colitis…and colorectal cancer? | journal = Infectious Agents and Cancer | volume = 13 | pages = 1 | date = 2018 | pmid = 29308085 | pmc = 5753485 | doi = 10.1186/s13027-017-0172-3 | doi-access = free }}</ref> {{clear}}
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