Editing Sugar substitute (section)

===Sucralose===
{{Main|Sucralose}}
The world's most commonly used artificial sweetener,<ref name=yahoo/> sucralose is a chlorinated sugar that is about 600 times sweeter than sugar. It is produced from sucrose when three chlorine atoms replace three [[hydroxyl group]]s. It is used in [[beverage]]s, [[frozen dessert]]s, [[chewing gum]], [[baked good]]s and other foods. Unlike other artificial sweeteners, it is stable when heated and can therefore be used in baked and fried goods. Discovered in 1976, the FDA approved sucralose for use in 1998.<ref>[https://www.fda.gov/bbs/topics/ANSWERS/ANS00859.html FDA approves new high-intensity sweetener sucralose] {{Webarchive|url=https://web.archive.org/web/20050520074139/https://www.fda.gov/bbs/topics/ANSWERS/ANS00859.html |date=20 May 2005 }}</ref>

Most of the controversy surrounding [[Splenda]], a sucralose sweetener, is focused not on safety but on its marketing. It has been marketed with the slogan, "Splenda is made from sugar, so it tastes like sugar." Sucralose is prepared from either of two sugars, sucrose or [[raffinose]]. With either base sugar, processing replaces three oxygen-hydrogen groups in the sugar molecule with three chlorine atoms.<ref name=livescience>{{cite web|url=http://www.livescience.com/health/070515_bad_sugar.html|title=Bitter Battle over Truth in Sweeteners|work=Live Science|date=15 May 2007|access-date=17 May 2007|archive-date=1 January 2011|archive-url=https://web.archive.org/web/20110101092255/http://www.livescience.com/health/070515_bad_sugar.html|url-status=live}}</ref>
The "Truth About Splenda" website was created in 2005 by the [[Sugar Association]], an organization representing [[sugar beet]] and [[sugar cane]] farmers in the United States,<ref>[http://www.truthaboutsplenda.com Truth About Splenda] {{Webarchive|url=https://web.archive.org/web/20050422015246/http://truthaboutsplenda.com/ |date=22 April 2005 }}, Sugar Association website</ref> to provide its view of sucralose. In December 2004, five separate false-advertising claims were filed by the Sugar Association against Splenda manufacturers [[Merisant]] and [[McNeil Nutritionals]] for claims made about Splenda related to the slogan, "Made from sugar, so it tastes like sugar." French courts ordered the slogan to no longer be used in France, while in the U.S., the case came to an undisclosed settlement during the trial.<ref name=livescience/>

There are few safety concerns pertaining to sucralose<ref>{{cite journal |vauthors=Grotz VL, Munro IC | title = An overview of the safety of sucralose | journal = [[Regulatory Toxicology and Pharmacology]] | volume = 55 | issue = 1 | pages = 1–5 | year = 2009 | pmid = 19464334 | doi = 10.1016/j.yrtph.2009.05.011 }}</ref> and the way sucralose is [[metabolism|metabolized]] suggests a reduced risk of toxicity. For example, sucralose is extremely insoluble in fat and, thus, does not accumulate in fatty tissues; sucralose also does not break down and will [[dechlorinate]] only under conditions that are not found during regular digestion (i.e., high heat applied to the powder form of the molecule).<ref name=Daniel/> Only about 15% of sucralose is absorbed by the body and most of it passes out of the body unchanged.<ref name=Daniel>{{cite journal |vauthors=Daniel JW, Renwick AG, Roberts A, Sims J |title=The metabolic fate of sucralose in rats |journal=[[Food Chem Toxicol]] |year=2000 |volume=38 |issue=S2 |pages=S115–S121 |doi=10.1016/S0278-6915(00)00034-X|pmid=10882824 }}</ref>

In 2017, sucralose was the most common sugar substitute used in the manufacture of foods and beverages; it had 30% of the global market, which was projected to be valued at $2.8 billion by 2021.<ref name="yahoo"/>