Editing Streptococcus pyogenes (section)

== Applications ==
=== Bionanotechnology ===
Many ''S. pyogenes'' proteins have unique properties, which have been harnessed in recent years to produce a highly specific "superglue"<ref name="pmid28550142">{{cite journal | vauthors = Howarth M | title = Smart superglue in streptococci? The proof is in the pulling | journal = The Journal of Biological Chemistry | volume = 292 | issue = 21 | pages = 8998–8999 | date = May 2017 | pmid = 28550142 | pmc = 5448131 | doi = 10.1074/jbc.H117.777466 | doi-access = free }}</ref><ref>{{cite journal | vauthors = Zakeri B, Fierer JO, Celik E, Chittock EC, Schwarz-Linek U, Moy VT, Howarth M | title = Peptide tag forming a rapid covalent bond to a protein, through engineering a bacterial adhesin | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 109 | issue = 12 | pages = E690–E697 | date = March 2012 | pmid = 22366317 | pmc = 3311370 | doi = 10.1073/pnas.1115485109 | doi-access = free | bibcode = 2012PNAS..109E.690Z }}</ref> and a route to enhance the effectiveness of [[antibody therapy (disambiguation)|antibody therapy]].<ref>{{cite journal | vauthors = Baruah K, Bowden TA, Krishna BA, Dwek RA, Crispin M, Scanlan CN | title = Selective deactivation of serum IgG: a general strategy for the enhancement of monoclonal antibody receptor interactions | journal = Journal of Molecular Biology | volume = 420 | issue = 1–2 | pages = 1–7 | date = June 2012 | pmid = 22484364 | pmc = 3437440 | doi = 10.1016/j.jmb.2012.04.002 }}</ref>

=== Genome editing ===
The [[CRISPR]] system from this organism<ref name="Deltcheva2011">{{cite journal | vauthors = Deltcheva E, Chylinski K, Sharma CM, Gonzales K, Chao Y, Pirzada ZA, Eckert MR, Vogel J, Charpentier E | display-authors = 6 | title = CRISPR RNA maturation by trans-encoded small RNA and host factor RNase III | journal = Nature | volume = 471 | issue = 7340 | pages = 602–607 | date = March 2011 | pmid = 21455174 | pmc = 3070239 | doi = 10.1038/nature09886 | bibcode = 2011Natur.471..602D }}</ref> that is used to recognize and destroy [[DNA]] from invading viruses, thus stopping the infection, was appropriated in 2012 for use as a genome-editing tool that could potentially alter any piece of DNA and later [[RNA]].<ref>{{Cite news|url=https://www.nytimes.com/2016/06/04/science/rna-c2c2-gene-editing-dna-crispr.html|title=Scientists Find Form of Crispr Gene Editing With New Capabilities| vauthors = Zimmer C |date=June 3, 2016|newspaper=The New York Times|issn=0362-4331|access-date=June 10, 2016}}</ref>