Editing Staphylococcus aureus (section)

=== Bacteremia ===
''Staphylococcus aureus'' is a leading cause of [[bloodstream infection]]s throughout much of the industrialized world.<ref name=Rasmussen2011>{{cite journal | vauthors = Rasmussen RV, Fowler VG, Skov R, Bruun NE | title = Future challenges and treatment of ''Staphylococcus aureus'' bacteremia with emphasis on MRSA | journal = Future Microbiology | volume = 6 | issue = 1 | pages = 43–56 | date = January 2011 | pmid = 21162635 | pmc = 3031962 | doi = 10.2217/fmb.10.155 }}</ref> Infection is generally associated with breaks in the skin or mucosal membranes due to surgery, injury, or use of [[intravascular]] devices such as [[cannula]]s, [[hemodialysis]] machines, or [[hypodermic needle]]s.<ref name=Tong2015/><ref name=Rasmussen2011/> Once the bacteria have entered the bloodstream, they can infect various organs, causing [[infective endocarditis]], [[septic arthritis]], and [[osteomyelitis]].<ref name=Rasmussen2011/> This disease is particularly prevalent and severe in the very young and very old.<ref name=Tong2015/>

Without antibiotic treatment, ''S. aureus'' bacteremia has a [[case fatality rate]] around 80%.<ref name=Tong2015/> With antibiotic treatment, case fatality rates range from 15% to 50% depending on the age and health of the patient, as well as the antibiotic resistance of the ''S. aureus'' strain.<ref name=Tong2015/>